Results 61 to 70 of about 82,891 (271)

Novel (Q)SAR models for prediction of reversible and time-dependent inhibition of cytochrome P450 enzymes

open access: yesFrontiers in Pharmacology
The 2020 FDA drug-drug interaction (DDI) guidance includes a consideration for metabolites with structural alerts for potential mechanism-based inhibition (MBI) and describes how this information may be used to determine whether in vitro studies need to ...
Sadegh Faramarzi   +6 more
doaj   +1 more source

Enhancing Information Technology On Organizational Performance Through In Cement Industry South Sulawesi

open access: yesJurnal Manajemen, 2023
This study aims to analyze and test the effect of information technology on organizational performance in the cement industry in South Sulawesi, namely PT Semen Tonasa and PT. Bosowa Cement.
Muhammad Kafrawi Yunus   +3 more
doaj   +1 more source

JEERP: Energy Aware Enterprise Resource Planning [PDF]

open access: yes, 2014
Ever increasing energy costs, and saving requirements, especially in enterprise contexts, are pushing the limits of Enterprise Resource Planning to better account energy, with component-level asset granularity.
Bonino, Dario   +3 more
core   +1 more source

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai   +7 more
wiley   +1 more source

Toxicological testing of syringaresinol and enterolignans

open access: yesCurrent Research in Toxicology, 2020
Lignans are secondary plant constituents with dibenzylbutane skeletons found in cereals, oilseeds, and nuts. Two members of this class, syringaresinol (Syr) and secoisolariciresinol (Seco), occur at relatively high levels in cereals and processed food ...
Verena Kirsch   +2 more
doaj   +1 more source

Race and Household Income are Associated with Disease Outcomes in Pediatric Patients with ANCA‐associated Vasculitis Hospitalized in the United States

open access: yesArthritis Care &Research, Accepted Article.
Objectives Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric anti‐neutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race/ethnicity and household income are associated with severe AAV disease and renal outcomes among ...
Roberto Alejandro Valdovinos   +2 more
wiley   +1 more source

Multifunctional Crushing and Piezoresistive Self‐Sensing in Conductive Epoxy/CNT‐Coated Polyetherimide TPMS Lattices

open access: yesAdvanced Engineering Materials, EarlyView.
This study reports lightweight polyetherimide triply periodic minimal surfaces lattices coated with carbon nanotube‐reinforced epoxy that combine mechanical robustness with self‐sensing. The conformal coating enhances stiffness, strength and energy absorption while enabling reliable strain monitoring.
A. Triay   +3 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

The Probabilistic Foundations of Surveillance Failure: From False Alerts to Structural Bias

open access: yesMathematics
Forensic statisticians have long debated whether searching large DNA databases undermines the evidential value of matches. Modern surveillance faces an exponentially harder problem: screening populations across thousands of attributes using threshold ...
Marco Pollanen
doaj   +1 more source

Investigating context-aware clues to assist navigation for visually impaired people [PDF]

open access: yes, 2002
It is estimated that 7.4 million people in Europe are visually impaired [1]. Limitations of traditional mobility aids (i.e. white canes and guide dogs) coupled with a proliferation of context-aware technologies (e.g.
Bradley, N.A., Dunlop, M.D.
core  

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