Results 121 to 130 of about 26,806,177 (307)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Homogenisation approaches for structural analysis of masonry structures

, 2006
Modern methodologies for the conservation of architectural heritage require structural analysis for the purpose of diagnosis and safety evaluation.
A. ZUCCHINI, P. LOURENCO, A. TRALLI, MILANI, GABRIELE   +3 more
core  

Mechanics of Optimal Structural Design for Extreme Loads to Peak System Responses [PDF]

, 2015
Over the past decades, with the development of modern manufacturing and information technology, demands of smart and economical structural designs have been increasing considerably. Central to this engineering issue is that a good structural design needs
Wang, Chien-Kai, Lo, Yuan-Lung, Hou, Kai-Shan, Zhao, Youjun, Cheng, Wei-Jen   +4 more
core  

Large scale structural analysis of protein tyrosine phosphatases

, 2009
Protein tyrosine phosphatases (PTPs) are essential regulators of signal transduction pathways, and control, together with protein tyrosine kinases (PTKs), the reversible phosphorylation of tyrosine residues. PTPs are, from a structural biology viewpoint,
Barr, A.J., Knapp, S.
core   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Performance of the Christchurch, New Zealand Cathedral during the M7.1 2010 Canterbury earthquake [PDF]

, 2014
The Catholic Cathedral is classified as a category 1 listed heritage building constructed largely of unreinforced stone masonry, and was significantly damaged in the recent Canterbury earthquakes of 2010 and 2011. In the 2010 event the building presented
Pender, Michael, Preciado, Adolfo, Lester, Jamie, Wang, Guojue, Ingham, Jason Maxwell   +4 more
core  

Machine learning and data-driven methods for steel constitutive modeling: a state-of-the-art review and validation

Discover Civil Engineering
In this work we develop and validate neural-network (NN) constitutive models for structural steels under monotonic and cyclic loading, using internal-variable inputs to encode path dependence. For monotonic tension at $$200-800^{\circ }C$$ (Kirby-Preston
Stefanos Voulgaris, Spyros Chandrinos, Ilias Chamatidis, Giorgos Kazakis, Pantelis Tsakalis, Chara Ch. Mitropoulou, Stelios K. Georgantzinos, Denis Istrati, Nikos D. Lagaros   +8 more
doaj   +1 more source

Experimental Analysis of Hybrid Panels Combining Flax/PLA Composite with UHMWPE and Steel Under Ballistic Impact

Journal of Natural Fibers
This study investigates the feasibility of substituting UHMWPE and steel with flax/PLA green composite in ballistic applications with the objective to increase sustainability and cost-effectiveness.
Liu Jiao-Wang, Samuel Charca, Borja Valverde, J.A. Loya, Carlos Santiuste   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source