Results 111 to 120 of about 3,177,476 (315)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Nonlinear Vibration of a Continuum Rotor with Transverse Electromagnetic and Bearing Excitations
Shock and Vibration, 2012 The nonlinear vibration of a rotor excited by transverse electromagnetic and oil-film forces is presented in this paper. The rotor-bearing system is modeled as a continuum beam which is loaded by a distributed electromagnetic load and is supported by two
Haiyang Luo, Yuefang Wang
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Economic Flexibility: A Structural Analysis [PDF]
, 2007 Economic flexibility is much discussed in the academic literature but has no agreed definition. In neoclassical economics, a flexible economy can be secured only by removing structural rigidities that block relative price movements and hamper the operation of markets – social structures are seen as a threat to flexibility.
openaire +2 more sources
Developing a QFD-Based design-integrated structural analysis methodology
, 2012 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Design of the mechanical components greatly depends on their expected structural performances.
Mobasseri, Seyed Omid
core
, 2014 In this paper a brief analysis of the most common masonry construction techniques in historical buildings and their evolution over the centuries is conducted.
DE GUGLIELMO, FABIO +2 more
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
A Structural Analysis of Population Graphs
ArXivThe format of graphing algorithms for genomic data has been a debate in recent biotechnology. In this paper, we discuss the construction of population graphs using said genomic data. We first examine the GENPOFAD distance measurement, developed by Joly et. al., and prove that this constitutes a metric function.
Ayers, Kimberly, Kooiker, Maxwell
openaire +4 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source