Recent developments of NeoCass the open source suite for structural sizing and aeroelastic analysis [PDF]
This paper presents the Matlab-based suite called NeoCASS (Next generation Conceptual Aero-Structural Sizing Suite), developed at the Department of Aerospace Engineering of Politecnico di Milano to be used especially in conceptual design phase.
Ricci S., Fonte F.
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Numerical And Experimental Investigations of Nonlinearity Behaviour In A Slender Cantilever Beam
Nonlinear problem is always occur in slender structures that are usually characterized by large displacements and rotations but small strains. Linear design assumption could lead to premature failure if the structure behaves nonlinearly.
Bahari A. R. +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Structural reliability of existing city bridges
Full probabilistic reliability analysis may be valuable for assessing existing structures. Measures for increasing the safety level are quite costly for existing structures and may be unnecessary when such a decision is grounded on a conservative ...
Hellebrandt, L. +3 more
core
Structural insights into complement regulation [PDF]
As an important tool of the innate immune system, the complement system rapidly recognizes and clears invading microbes and host debris. Furthermore, it stimulates B- and T-cell development through cross talks with the adaptive immune system.
Sub Crystal and Structural Chemistry +2 more
core
Influence of structural nonlinearities in stall-induced aeroelastic response of pitching airfoils
Stall-induced vibrations are a relevant aeroelastic problem for very flexible aero-structures. Helicopter blades, wind turbines, or other rotating components are severely inflicted to vibrate in stall condition during each revolution of its rotor ...
Pereira, Daniel A. +2 more
core +3 more sources
Glacios 2 Cryo-TEM and Smart EPU Software streamline Cryo-EM for drug design with higher throughput [PDF]
Koh Adrian +10 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Thermo Scientific Smart EPU Software: Towards autonomous screening [PDF]
Grollios Fanis +3 more
doaj +1 more source

