Results 91 to 100 of about 6,922,711 (307)

Identifying RNA contacts from SHAPE-MaP by partial correlation analysis [PDF]

open access: yes, 2014
In a recent paper Siegfried et al. published a new sequence-based structural RNA assay that utilizes mutational profiling to detect base pairing (MaP).
Doudna, Jennifer   +2 more
core   +3 more sources

Survey of Finite Element Method-Based Real-Time Simulations

open access: yesApplied Sciences, 2019
The finite element method (FEM) has deservedly gained the reputation of the most powerful, highly efficient, and versatile numerical method in the field of structural analysis.
Dragan Marinkovic, Manfred Zehn
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Intelligent Structure Searching and Designs for Nanoclusters: Effective Units in Atomic Manufacturing

open access: yesAdvanced Intelligent Systems
Clusters, an aggregation of several to thousands of atoms, molecules, or ions, are the building blocks of novel functional materials by atomic manufacturing and exhibit excellent applications in catalysis, quantum information, and nanomedicine.
Junfeng Gao   +7 more
doaj   +1 more source

Influence of Failure Strain of Different Aluminium Alloys on Dynamic Problems

open access: yesEngineering Transactions, 2014
In this work an experimental-numerical methodology is devised for analyzing ductile fracture of two aluminum alloys under different values of stress triaxiality (0.2 ≤ η ≤ 1.2) and Lode parameter (−1 ≤ μ ≤ 0).
Marcos RODRIGUEZ-MILL´AN   +4 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Fatigue and Structural Analysis of Azimuth Thruster Assembly [PDF]

open access: yes, 2016
Composite is stated as constituent of two or more materials which retain their own physical and chemical property during the time of application, but produce a component which inherent the properties of its constituent materials and makes it better for ...
Ambadekar, P. (Prashant)   +4 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Aircraft Conceptual Structural Design Using the AMMIT Structural Analysis Tool [PDF]

open access: yes
Aircraft conceptual structural design is the process of developing and refining an idea for an aircraft into a feasible structural design. The process typically involves multiple evaluations of a single configuration and can require designers to examine ...
Horvath, Bryce L.
core   +1 more source

An interactive graphics system to facilitate finite element structural analysis [PDF]

open access: yes, 1973
The characteristics of an interactive graphics systems to facilitate the finite element method of structural analysis are described. The finite element model analysis consists of three phases: (1) preprocessing (model generation), (2) problem solution ...
Burk, R. C., Held, F. H.
core   +1 more source

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