Results 71 to 80 of about 26,806,177 (307)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Structural and stress analysis /
, 2005 Structural analysis is the corner stone of civil engineering and all students must obtain a thorough understanding of the techniques available to analyse and predict stress in any structure.
Megson, T. H. G.(Thomas Henry Gordon)
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Interactive Structural Analysis
, 2011 This paper re-approaches structural engineering through an interactive perspective by introducing a series of tools that concatenate parametric design with structural analysis, thus achieving interoperability between form and its structural performance ...
O. Georgiou
core
An Analysis of Tournament Structure
CoRR, 2016 This paper explores a novel way for analyzing the tournament structures to find a best suitable one for the tournament under consideration. It concerns about three aspects such as tournament conducting cost, competitiveness development and ranking precision. It then proposes a new method using progress tree to detect potential throwaway matches.
Nhien Pham Hoang Bao, Hiroyuki Iida
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Structural studies of human cell surface receptors: On low-density lipoprotein receptor-related protein 1 and epidermal growth factor receptors 2 and 3 [PDF]
, 2017 The elucidation of proteins’ structure and function is of great importance for the understanding of disease triggering mechanisms and for the development of new drugs. In this thesis, different biophysical and biochemical techniques were employed to gain
Sub Crystal and Structural Chemistry +2 more
core
Damage identification on a large-scale wind turbine rotor blade using sample-based deterministic model updating [PDF]
Wind Energy ScienceWind turbine rotor blades are among the most critical components of wind turbines, with their structural integrity directly affecting reliability, lifetime, and maintenance costs.
M. Wolniak +6 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source