Results 71 to 80 of about 6,922,711 (307)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structural analysis applications [PDF]

open access: yes
An account is given of the application of computer codes for the efficient conduct of three-dimensional inelastic analyses to aircraft gas turbine combustor, turbine blade, and turbine stator vane components.
Mcknight, R. L.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Damage identification on a large-scale wind turbine rotor blade using sample-based deterministic model updating [PDF]

open access: yesWind Energy Science
Wind turbine rotor blades are among the most critical components of wind turbines, with their structural integrity directly affecting reliability, lifetime, and maintenance costs.
M. Wolniak   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Computational engine structural analysis [PDF]

open access: yes
A significant research activity at the NASA Lewis Research Center is the computational simulation of complex multidisciplinary engine structural problems.
Chamis, C. C., Johns, R. H.
core   +1 more source

Private analysis of graph structure [PDF]

open access: yesProceedings of the VLDB Endowment, 2011
We present efficient algorithms for releasing useful statistics about graph data while providing rigorous privacy guarantees. Our algorithms work on data sets that consist of relationships between individuals, such as social ties or email communication.
Vishesh Karwa   +3 more
openaire   +1 more source

A new method for ship inner shell optimization based on parametric technique

open access: yesInternational Journal of Naval Architecture and Ocean Engineering, 2015
A new method for ship Inner Shell optimization, which is called Parametric Inner Shell Optimization Method (PISOM), is presented in this paper in order to improve both hull performance and design efficiency of transport ship.
Yan-Yun Yu, Yan Lin, Ming Chen, Kai Li
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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