Results 51 to 60 of about 26,806,177 (307)

Productivity and Reallocation: Evidence from the Universe of Italian Firms [PDF]

International Productivity Monitor, 2017
This article investigates the contribution of allocative efficiency to aggregate labour productivity growth in Italy between 2005 and 2013. Exploiting a unique dataset that covers the universe of firms, we find that allocative efficiency increased during
Andrea Linarello, Andrea Petrella
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural and functional studies on Nod Like Receptors: insights into NAIP/NLRC4 inflammasome formation [PDF]

, 2013
Our immune system is under constant attack of invading pathogens. The initiation of an appropriate immune response that leads to clearance of these microorganisms and infected cells is dependent on the ability of the immune system to discern between ...
Sub Crystal and Structural Chemistry, Crystal and Structural Chemistry, Halff, E.F.   +2 more
core  

Embedded feature selection using dual-network architecture

Machine Learning with Applications
Feature selection is essential for eliminating noise, reducing redundancy, simplifying computational complexity, and lowering data collection and processing costs.
Abderrahim Abbassi, Arved Dörpinghaus, Niklas Römgens, Tanja Grießmann, Raimund Rolfes   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A Spatial Euler-Bernoulli Beam Element for Rigid-Flexible Coupling Dynamic Analysis of Flexible Structures

Shock and Vibration, 2015
A two-node spatial beam element with the Euler-Bernoulli assumption is developed for the nonlinear dynamic analysis of slender beams undergoing arbitrary rigid motions and large deformations.
Zhigang Zhang, Zhaohui Qi, Zhigang Wu, Huiqing Fang   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An efficient numerical model to predict fatigue damage behavior of carbon composites accounting for variations in ply thickness

Materials & Design
Thin-ply (TP) laminates represent a significant advancement in the composite industry, primarily due to their enhanced mechanical performance and increased resistance to damage.
M. Tariq, S. Scheffler, P.M. Anilkumar, C. Rolffs, R. Rolfes   +4 more
doaj   +1 more source

Partitioned Strong Coupling of Discrete Elements with Large Deformation Structural Finite Elements to Model Impact on Highly Flexible Tension Structures

Advances in Civil Engineering, 2020
This article presents a staggered approach to couple the interaction of very flexible tension structures with large deformations, described with the finite element method (FEM), and objects undergoing large, complex, and arbitrary motions discretized ...
Klaus Bernd Sautter, Tobias Teschemacher, Miguel Ángel Celigueta, Philipp Bucher, Kai-Uwe Bletzinger, Roland Wüchner   +5 more
doaj   +1 more source

Structural Analysis of Tn5

Cold Spring Harbor Symposia on Quantitative Biology, 1981
Nucleotide sequences have been determined for the 1.5-kb inverted repeats of Tn5 and for their junctions with the central unique region and with host DNA. The primary findings stemming from this analysis are: 1. Integration of Tn5 is accompanied by the duplication of 9 bp of host DNA. 2.
E A, Auerswald, G, Ludwig, H, Schaller
openaire   +2 more sources