Results 41 to 50 of about 3,177,476 (315)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Research on the Load Bearing and Impact Resistance of a Novel Structure Exhibiting Both Positive and Negative Poisson’s Ratios

open access: yesShock and Vibration
A ship equipment pedestal is a structure that connects power equipment to a hull. It must have a high load-bearing capacity and the ability to withstand large impact loads.
Xidong Zhang   +4 more
doaj   +1 more source

A two-stage framework for identifying and characterizing wind turbine noise data and its validation by listening tests [PDF]

open access: yesWind Energy Science
The reliable identification of acoustically dominant wind turbine noise in field measurements is essential for analysing source-specific noise characteristics and sound propagation under real atmospheric conditions. Long-term acoustic data sets typically
S. Könecke   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Experimental and Numerical Simulation Study of Water Infiltration Impact on Soil-Pile Interaction in Expansive Soil

open access: yesGeofluids
A laboratory model of a single pile embedded in Nanyang expansive soil and subjected to water infiltration is applied in this study to examine the interaction between the expansive soil and pile foundation upon water infiltration. The soil matric suction
Waleed Awadalseed   +5 more
doaj   +1 more source

Artificial Neural Networks Based Friction Law for Elastomeric Materials Applied in Finite Element Sliding Contact Simulations

open access: yesComplexity, 2018
A realistic characterization of the frictional behaviour of materials and mechanical systems is of prime importance for the assessment of their contact interaction properties, especially in the context of undesired temperature rise or intensive wear ...
Aleksandra Serafińska   +2 more
doaj   +1 more source

Analysis of the behaviour of aircraft and aerospace structural elements under impact [PDF]

open access: yes, 2008
The Group “Dynamics and Fracture of Structural Elements” offers its experience in Solid Mechanics analysis for the study of the behaviour of structural elements subjected to impact loads.
Zaera Polo, Ramón Eulalio   +3 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Productivity and Reallocation: Evidence from the Universe of Italian Firms [PDF]

open access: yesInternational Productivity Monitor, 2017
This article investigates the contribution of allocative efficiency to aggregate labour productivity growth in Italy between 2005 and 2013. Exploiting a unique dataset that covers the universe of firms, we find that allocative efficiency increased during
Andrea Linarello, Andrea Petrella
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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