Results 41 to 50 of about 26,806,177 (307)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Sorting out Sortilins: structural studies on the VPS10 family [PDF]

open access: yes, 2017
The topic of this dissertation is the structural characterization of the VPS10 receptors Sortilin and SorCS2, as well as their interactions with proneurotrophins.
Sub Crystal and Structural Chemistry   +2 more
core  

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Research on the Load Bearing and Impact Resistance of a Novel Structure Exhibiting Both Positive and Negative Poisson’s Ratios

open access: yesShock and Vibration
A ship equipment pedestal is a structure that connects power equipment to a hull. It must have a high load-bearing capacity and the ability to withstand large impact loads.
Xidong Zhang   +4 more
doaj   +1 more source

A two-stage framework for identifying and characterizing wind turbine noise data and its validation by listening tests [PDF]

open access: yesWind Energy Science
The reliable identification of acoustically dominant wind turbine noise in field measurements is essential for analysing source-specific noise characteristics and sound propagation under real atmospheric conditions. Long-term acoustic data sets typically
S. Könecke   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Experimental and Numerical Simulation Study of Water Infiltration Impact on Soil-Pile Interaction in Expansive Soil

open access: yesGeofluids
A laboratory model of a single pile embedded in Nanyang expansive soil and subjected to water infiltration is applied in this study to examine the interaction between the expansive soil and pile foundation upon water infiltration. The soil matric suction
Waleed Awadalseed   +5 more
doaj   +1 more source

Artificial Neural Networks Based Friction Law for Elastomeric Materials Applied in Finite Element Sliding Contact Simulations

open access: yesComplexity, 2018
A realistic characterization of the frictional behaviour of materials and mechanical systems is of prime importance for the assessment of their contact interaction properties, especially in the context of undesired temperature rise or intensive wear ...
Aleksandra Serafińska   +2 more
doaj   +1 more source

Structural Analysis of Bikunin Glycosaminoglycan [PDF]

open access: yesJournal of the American Chemical Society, 2008
The structure of an intact glycosaminoglycan (GAG) chain of the bikunin proteoglycan (PG) was analyzed using a combined top-down and bottom-up sequencing strategy. PGs are proteins with one or more linear, high-molecular weight, sulfated GAG polysaccharides O-linked to serine or threonine residues.
CHI L   +8 more
openaire   +5 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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