Results 101 to 110 of about 1,236,466 (297)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Structural, Mechanical, and Electronic Properties of High-Hardness Silicon Tetranitride

Molecules
Materials with high hardness are critical for industrial and aerospace applications, prompting the search for novel compounds with robust covalent networks.
Lulu Liu, Jiacheng Qi, Chi Ding, Dinghui Wang, Shoutao Zhang   +4 more
doaj   +1 more source

Structural, Mechanical and Optical Properties of Plasma-chemical Si-C-N Films [PDF]

Журнал нано- та електронної фізики, 2014
An influence of the substrate temperature in the range of 40-400 °C on the properties of the Si-C-N films deposited by plasma enhanced chemical vapor deposition (PECVD) technique using hexamethyldisilazane is analyzed.
A.O. Kozak, V.I. Ivashchenko, O.K. Porada, L.A. Ivashchenko, T.V. Tomila   +4 more
doaj  

STRUCTURAL AND MECHANICAL PROPERTIES OF THE FATTY COMPOSITION WITH USAGE OF INULIN AND PASTE MASSES BASED ON IT

Вестник Северо-Кавказского федерального университета, 2022
Development of technology of meat products with reduced fat content with usage of natural cereal ingredients is rather actually nowadays. Introduction of chicory inulin basedfat compositions instead offat stuff to paste receipt will significant improve ...
Evgeniya Smolko, Lydmila Barybina, Valentina Kulikova, Olga Kozhevnikova   +3 more
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Structural and Mechanical Properties of Nanocrystalline Fe60Al30Cu10 (at.%) Powders Prepared by Mechanical Alloying

Gazi Üniversitesi Fen Bilimleri Dergisi, 2019
In the present study, the nanostructured Fe(Al,Cu) solid solution was synthesized by mechanical alloying (MA) process of the elemental powders. The powder mixtures were milled in a planetary ball mill for various periods of time, up to 50 h.
Barış AVAR, Tuncay ŞİMŞEK, Musa GÖĞEBAKAN   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Carbon nanotubes for epoxy Nanocomposites: a review on recent developments [PDF]

, 2012
Carbon nanotubes (CNTs) are one of the strongest and stiffest engineering fibres. Due to their unique combination of chemical and physical properties at an incredibly small size, they possess great potential to be used as nanofillers for many structural ...
Inam, Fawad, Luhyna, Nataliia
core  

Growth and properties of few-layer graphene prepared by chemical vapor deposition

, 2009
The structure, and electrical, mechanical and optical properties of few-layer graphene (FLG) synthesized by chemical vapor deposition (CVD) on a Ni coated substrate were studied. Atomic resolution transmission electron microscope (TEM) images show highly
Berger, Blake, Bolotin, Cai, Chae, Date, Dikin, Echtermeyer, Eda, Emtsev, Ferrari, Geim, Geng, Haluška, Hye Jin Park, Jannik Meyer, Johansson, Kim, Li, Li, Meyer, Meyer, Nair, Novoselov, Obraztsov, Park, Park, Phani, Reina, Reina, Sakamoto, Seiler, Siegmar Roth, Stankovich, Stoller, Tung, Viera Skákalová, Vázquez de Parga, Wang, Wei, Yang, Yu   +41 more
core   +1 more source