Results 101 to 110 of about 425,057 (313)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
METHODS OF REGULATING PHYSICAL PROPERTIES OF DOUGH USING PHYTOEXTRACTS
Harčova Nauka ì Tehnologìâ, 2018 This paper considers the prospects of using phytomaterials to solve the problems of baking industry, caused by the instability and defects of wheat flour, and analyses the main methods of regulating structural and mechanical properties of wheat dough and
T. Lebedenko +3 more
doaj +1 more source
Variation of mechanical properties in a multi-pass weld measured using digital image correlation [PDF]
, 2009 As part of a programme investigating the structural integrity of welds, the Digital Image Correlation (DIC)technique was used to obtain the full-field strain distribution during tensile testing of cross-weld specimens cutfrom a multi-pass girth welded
Bouchard, Peter +7 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Gazi Üniversitesi Fen Bilimleri Dergisi, 2019 In the present study, the nanostructured Fe(Al,Cu) solid solution was synthesized by mechanical alloying (MA) process of the elemental powders. The powder mixtures were milled in a planetary ball mill for various periods of time, up to 50 h.
Barış AVAR +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Nanocomposites for vehicle structural applications [PDF]
, 2011 Advancements in the nanotechnology industry promise to offer improvements in capabilities across a spectrum of applications. This is of immense strategic importance to the high performance sector which has historically leveraged technological advances ...
Sachse, Sophia +6 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 2013 Includes abstract.Includes bibliographical references.Current replacements for diseased arteries include autologous and artificial grafts. The availability of autologous grafts is limited and artificial grafts tend to fail when applied to small calibre ...
Khatib, Rodaina Omar
core
Fabrication and mechanical testing of a new sandwich structure with carbon fiber network core. [PDF]
, 2010 The aim is the fabrication and mechanical testing of sandwich structures including a new core material known as fiber network sandwich materials.
Bouvet, Christophe +4 more
core +1 more source