Results 111 to 120 of about 1,236,466 (297)

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

METHODS OF REGULATING PHYSICAL PROPERTIES OF DOUGH USING PHYTOEXTRACTS

Harčova Nauka ì Tehnologìâ, 2018
This paper considers the prospects of using phytomaterials to solve the problems of baking industry, caused by the instability and defects of wheat flour, and analyses the main methods of regulating structural and mechanical properties of wheat dough and
T. Lebedenko, H. Korkach, V. Kozhevnikova, T. Novichkova   +3 more
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Materials data handbooks prepared for aluminum alloys 2014, 2219, and 5456, and stainless steel alloy 301 [PDF]

, 1967
Materials data handbooks summarize all presently known properties of commercially available structural aluminum alloys 2014, 2219, and 5456 and structural stainless steel alloy 301.

core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Structural and Mechanical Properties of Orthorhombic Libeh3: AB-Initio Study

Annals of West University of Timisoara: Physics
The structural parameters and the elastic properties of orthorhombic LiBeH3 material were predicted theoretically using the density functional theory (DFT).
Rahrah M., Lebga N., Latreche A., Daoud S., Benmakhlouf A.   +4 more
doaj   +1 more source

Additive manufacturing of carbon nanocomposites for structural applications

Journal of Materials Research and Technology
Additive manufacturing (AM), also known as 3D printing, has attracted a lot of attention in science and technology in recent years. Improvement in AM processes and materials are necessary, particularly for structural and load-bearing components in ...
Muhammed Hisham, Muhammed Shebeeb C, Dileep C, Liya Jacob, Haider Butt   +4 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Structural, morphological, mechanical and thermal properties of PMMA/SiC composites

Polymers and Polymer Composites
In this study, silicon carbide (SiC) microfibers were added as reinforcement to improve the thermomechanical properties of poly (methyl methacrylate) polymer, PMMA, since this type of composite has not been explored well enough so far.
Vera Obradović, Ivana O. Mladenović, Marija M. Vuksanović, Željko Radovanović, Vladislav Jovanov   +4 more
doaj   +1 more source