Results 31 to 40 of about 354,030 (240)

Comparative analysis of different finite element models of the soil-buried arch bridge interaction [PDF]

Građevinski Materijali i Konstrukcije, 2019
Comparative analysis is made of different finite element models of a buried arch bridge which is constructed from precast concrete elements. Two static schemes of the bridge structure are considered - a static scheme of rigid connection between all ...
Kazakov Konstantin, Mihova Lena, Partov Doncho   +2 more
doaj  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Nonlinear seismic analysis of masonry infilled RC frame structures [PDF]

Građevinski Materijali i Konstrukcije, 2019
Structures composed of different substructures and materials are a subject of great research and expert interest. It is the purpose of this research to develop an engineering approach for evaluation of seismic demands and to apply the methodology to ...
Mahmud Emin, Bonev Zdravko, Abdulahad Emad   +2 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Structures and Architecture [PDF]

From Wood to Tree explores designing with wood’s natural degradation processes. This case-study proposes a sustainable approach for reintegrating processed preprocessed lumber into forest ecosystems, highlighting the importance of deadwood in supporting nutrient cycling, fostering fungal growth, enhancing soil health and providing habitats for saplings,
Rinke, Mario, Hvejsel, Marie Frier
  +4 more sources

The impact of vibration on buildings: Problems and solutions [PDF]

E3S Web of Conferences
The article presents a comprehensive overview of a study investigating the influence of soil-foundation interaction on the natural frequencies and vibration safety of reinforced concrete cellular and frame buildings.
Kovrova Viktoriia, Volkova Viktoriia, Pakrastins Leonids   +2 more
doaj   +1 more source

Model Experimental Study of Carbon Fiber Heating Wire for Deicing and Snow Melting on a Bridge Deck

Advances in Civil Engineering, 2020
In order to use the carbon fiber heating wire more efficiently and safely, the influence of the built-in carbon fiber heating wires (CFHWs) on the temperature changes of the bridge deck is studied in this paper.
Yan Tan, Yuntao Zhu, Henglin Xiao
doaj   +1 more source