Results 51 to 60 of about 650,868 (292)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Background Partitioning of a protein into structural components, known as domains, is an important initial step in protein classification and for functional and evolutionary studies.
Bourne Philip E +2 more
doaj +1 more source
Stop bashing givenness : a note on Elke Kasimir´s "questions-answers test and givenness" [PDF]
Elke Kasimir´s paper (in this volume) argues against employing the notion of Givenness in the explanation of accent assignment. I will claim that the arguments against Givenness put forward by Kasimir are inconclusive because they beg the question of the
Weskott, Thomas
core
Student Mastery of Engineering with Design Review [PDF]
Traditional structural engineering pedagogy has consisted of students preparing for class by reading a textbook, followed by a professor giving a lecture, followed by students doing individual homework. Students received feedback in terms of a grade from
Campbell, Michael C., Hill, Aaron T.
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The synthesis of 2-[2-carboxymethylthio-2-(4-chlorophenyl) ethyl]-2-(4-chlorophenyl) - 4-thiazolidinone (1) from p, p'- dichlorochalcone using thioglycollic acid in the presence of ammonium carbonate is described.
Roger Dommisse +5 more
doaj +1 more source
Chromosomal assignment and genomic structure of Il15
Interleukin-15 (IL-15) is a novel cytokine whose effects on T-cell activation and proliferation are similar to those of interleukin-2 (IL-2), presumably because IL-15 utilizes the beta and gamma chains of the IL-2 receptor. Murine IL-15 cDNA and genomic clones were isolated and characterized.
Dirk M. Anderson +11 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Identifying structural domains of proteins using clustering
Background Protein structures are comprised of modular elements known as domains. These units are used and re-used over and over in nature, and usually serve some particular function in the structure. Thus it is useful to be able to break up a protein of
Feldman Howard J
doaj +1 more source
Snow Cover in Alaska: Comprehensive Review [PDF]
This report presents the results of a statistical analysis of snow cover in Alaska using historical data acquired from the Global Historical Climate Network.
Folan, Tommy +4 more
core

