Results 41 to 50 of about 647,700 (302)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Nonlinear Modeling of Structural Breaks Concerning Money Demand Function in Iran Using Fuzzy Approach [PDF]
پژوهشهای اقتصادی, 2014 The main purpose of this paper is to introduce a method for more accurately measurement of structural breaks’ impacts of money demand function using fuzzy set approach.
Esmaiel Abounoori, Behnam Shahryar
doaj
East Asian Economic Review, 2016 This paper quantitatively compares the intrinsic features of the daily USD-GBP exchange rates in two different periods, the 1920s and the 2010s, under the same freely floating exchange rate system.
Young Wook Han
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A TEST OF THE EFFICIENCY OF THE FOREIGN EXCHANGE MARKET IN INDONESIA
Buletin Ekonomi Moneter dan Perbankan, 2019 We test whether the Indonesian foreign exchange market is efficient. Since empirical evidence has been inconclusive, we employ a new generalized autoregressive conditional heteroskedasticity–based unit root test to examine the Efficient Market Hypothesis
Bernard Njindan Iyke
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The structure and clustering of Lyman-break galaxies [PDF]
Monthly Notices of the Royal Astronomical Society, 1999 The number density and clustering properties of Lyman-break galaxies (LBGs) are consistent with them being the central galaxies of the most massive dark halos present at z~3. This conclusion holds in all currently popular hierarchical models for structure formation, and is almost independent of the global cosmological parameters. We examine whether the
Mo, H. J. +2 more
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Structural Breaks, Energy Consumption and Economic Growth in Iran (1967-2005) [PDF]
پژوهشهای اقتصادی, 2009 Understanding the different aspects of the relationship between energy consumption and economic growth can outstandingly help to adopt appropriate policies in energy sector. Structural breaks and regime shifts may affect the above relationship. Therefore,
Davood Behbudi, Hossien Asgharpour,
doaj