Results 51 to 60 of about 3,581,851 (300)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Detrending procedures and cointegration testing: ECM tests under structural breaks [PDF]

open access: yes, 1998
It is well known that all the test for unit roots and cointegration depend on the deterministic elements that are in mean of the variables; constant, trend, breaks, outliers, segmented trends, etc. This is a serious inconvenient for empirical work.
Escribano, Álvaro, Arranz, Miguel A.
core   +1 more source

Structural Breaks, Energy Consumption and Economic Growth in Iran (1967-2005) [PDF]

open access: yesپژوهشهای اقتصادی, 2009
Understanding the different aspects of the relationship between energy consumption and economic growth can outstandingly help to adopt appropriate policies in energy sector. Structural breaks and regime shifts may affect the above relationship. Therefore,
Davood Behbudi, Hossien Asgharpour,
doaj  

Semi-Metric Portfolio Optimization: A New Algorithm Reducing Simultaneous Asset Shocks

open access: yesEconometrics, 2023
This paper proposes a new method for financial portfolio optimization based on reducing simultaneous asset shocks across a collection of assets.
Nick James, Max Menzies, Jennifer Chan
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

1.An Examination of Malaysia’s Structural Breaks Vis-À-Vis Japan and the USA [PDF]

open access: yesPakistan Journal of Commerce and Social Sciences, 2012
This paper primarily examines whether Malaysia has had experienced any structural breaks in comparison with its main two trading partners, namely the USA and Japan in 1970s, 1980s, 1990s and 2000s.
Md. Wahid Murad   +3 more
doaj  

Static and Dynamic Structural Symmetry Breaking [PDF]

open access: yes, 2006
We reconsider the idea of structural symmetry breaking (SSB) for constraint satisfaction problems (CSPs). We show that the dynamic dominance checks used in symmetry breaking by dominance-detection search for CSPs with piecewise variable and value symmetries have a static counterpart: there exists a set of constraints that can be posted at the root node
Pierre Flener   +3 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Structural breaks in the cattle price series in the State of São Paulo, Brazil

open access: yesEconomia Aplicada, 2016
This paper examines the existence of structural breaks in the live cattle price series in the state of São Paulo between 1954 and 2012. Due to the importance of cattle ranching in Brazil and the characteristics of the series of cattle price, such as ...
Cláudio Shikida   +2 more
doaj   +1 more source

A New Nonlinear Specification of Structural Breaks for Money Demand in Iran [PDF]

open access: yesIranian Journal of Economic Studies, 2014
In a structural time series regression model, binary variables have been used to quantify qualitative or categorical quantitative events such as politic and economic structural breaks, regions, age groups and etc. The use of the binary dummy variables is
Esmaiel Abounoori, Behnam Shahriyar
doaj   +1 more source

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