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Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Detrending procedures and cointegration testing: ECM tests under structural breaks [PDF]
It is well known that all the test for unit roots and cointegration depend on the deterministic elements that are in mean of the variables; constant, trend, breaks, outliers, segmented trends, etc. This is a serious inconvenient for empirical work.
Escribano, Álvaro, Arranz, Miguel A.
core +1 more source
Structural Breaks, Energy Consumption and Economic Growth in Iran (1967-2005) [PDF]
Understanding the different aspects of the relationship between energy consumption and economic growth can outstandingly help to adopt appropriate policies in energy sector. Structural breaks and regime shifts may affect the above relationship. Therefore,
Davood Behbudi, Hossien Asgharpour,
doaj
Semi-Metric Portfolio Optimization: A New Algorithm Reducing Simultaneous Asset Shocks
This paper proposes a new method for financial portfolio optimization based on reducing simultaneous asset shocks across a collection of assets.
Nick James, Max Menzies, Jennifer Chan
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
1.An Examination of Malaysia’s Structural Breaks Vis-À-Vis Japan and the USA [PDF]
This paper primarily examines whether Malaysia has had experienced any structural breaks in comparison with its main two trading partners, namely the USA and Japan in 1970s, 1980s, 1990s and 2000s.
Md. Wahid Murad +3 more
doaj
Static and Dynamic Structural Symmetry Breaking [PDF]
We reconsider the idea of structural symmetry breaking (SSB) for constraint satisfaction problems (CSPs). We show that the dynamic dominance checks used in symmetry breaking by dominance-detection search for CSPs with piecewise variable and value symmetries have a static counterpart: there exists a set of constraints that can be posted at the root node
Pierre Flener +3 more
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Structural breaks in the cattle price series in the State of São Paulo, Brazil
This paper examines the existence of structural breaks in the live cattle price series in the state of São Paulo between 1954 and 2012. Due to the importance of cattle ranching in Brazil and the characteristics of the series of cattle price, such as ...
Cláudio Shikida +2 more
doaj +1 more source
A New Nonlinear Specification of Structural Breaks for Money Demand in Iran [PDF]
In a structural time series regression model, binary variables have been used to quantify qualitative or categorical quantitative events such as politic and economic structural breaks, regions, age groups and etc. The use of the binary dummy variables is
Esmaiel Abounoori, Behnam Shahriyar
doaj +1 more source

