Results 71 to 80 of about 647,700 (302)

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Structural Breaks in Military Expenditures: Evidence for Egypt, Israel, Jordan and Syria [PDF]

open access: yes
This paper endogenously determines the timing of structural breaks in military expenditures and military burdens for the major parties involved in the Israeli-Arab conflict, namely Egypt, Israel, Jordan, and Syria over the period 1960-2004.
Aamer Abu-Qarn, Suleiman Abu-Bader
core   +3 more sources

Structural Breaks and Volatility Spillover in South Asian Economies

open access: yesSEISENSE Journal of Management, 2020
Purpose - This study examines the volatility spillovers in the presence of structural breaks with specific reference to South Asian Capital markets.
Hafiz Rauf Iqbal   +2 more
doaj   +1 more source

Breaking the structure of MaMaDroid

open access: yesExpert Systems with Applications, 2023
Harel Berger   +3 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Unit Roots and Structural Breaks: A Survey of the Literature [PDF]

open access: yes
Since Perron (1989) the time series literature has emphasised the importance of testing for structural breaks in typical economic data sets and pronounced the implications of structural breaks when testing for unit root processes. In this paper we survey
Joseph P. Byrne, Roger Perman
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Is It the Natural Rate Hypothesis or the Hysteresis Hypothesis for Unemployment Rates in Newly Industrialized Economies?

open access: yesComparative Economic Research, 2019
The focus of our study is on determining whether unemployment rates in 8 New Industrialized Economies conform to the natural rate hypothesis or the hysteresis hypothesis.
Dieu Nsenga   +4 more
doaj   +1 more source

Bayesian Model Averaging and Identification of Structural Breaks in Time Series [PDF]

open access: yes
Bayesian model averaging is used for testing for multiple break points in uni- variate series using conjugate normal-gamma priors. This approach can test for the number of structural breaks and produce posterior probabilities for a break at each point in
Balcombe, Kelvin   +2 more
core   +1 more source

How Costly is it to Ignore Breaks when Forecasting the Direction of a Time Series? [PDF]

open access: yes, 2003
Empirical evidence suggests that many macroeconomic and financial time-series are subject to occasional structural breaks. In this paper we present analytical results quantifying the effects of such breaks on the correlation between the forecast and ...
Pesaran, M. Hashem, Timmermann, Allan
core   +2 more sources

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