Results 1 to 10 of about 2,083,635 (328)

Structural Flyby Characterization of Nanoporosity [PDF]

open access: yesphysica status solidi (c), 2004
Recently, Ferreira da Silva et al. [3] have performed a gradient pattern analysis of a canonical sample set (CSS) of scanning force microscopy (SFM) images of p-Si.
Andersen   +8 more
core   +2 more sources

Structural Characterization of Pinnatoxin Isomers. [PDF]

open access: yesMar Drugs
Pinnatoxins, a group of marine biotoxins primarily produced by the dinoflagellate Vulcanodinium rugosum, have garnered significant attention due to their potent toxic effects and widespread distribution in marine ecosystems. LC–MS analysis of shellfish and V. rugosum cultures revealed the presence of previously unidentified isomers of pinnatoxins D, E,
Selwood AI   +5 more
europepmc   +4 more sources

Unusual nonlinear switching in branched carbon nanotube nanocomposites

open access: yesScientific Reports, 2023
In this experimental study, we investigate the nonlinear dynamic response of nanocomposite beams composed of polybutylene terephthalate (PBT) and branched carbon nanotubes (bCNTs).
Walter Lacarbonara   +6 more
doaj   +1 more source

Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding

open access: yesNature Communications, 2023
Hydroxycarboxylic acid receptors (HCA) are expressed in various tissues and immune cells. HCA2 and its agonist are thus important targets for treating inflammatory and metabolic disorders.
Shota Suzuki   +5 more
doaj   +1 more source

Epigenetic mechanisms to propagate histone acetylation by p300/CBP

open access: yesNature Communications, 2023
Histone acetylation is important for the activation of gene transcription but little is known about its direct read/write mechanisms. Here, we report cryogenic electron microscopy structures in which a p300/CREB-binding protein (CBP) multidomain monomer ...
Masaki Kikuchi   +8 more
doaj   +1 more source

Structural Modification and Biological Activity of Polysaccharides

open access: yesMolecules, 2023
Natural polysaccharides are macromolecular substances with a wide range of biological activities. The structural modification of polysaccharides by chemical means can enhance their biological activity.
Ting Zhao   +9 more
doaj   +1 more source

Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming

open access: yesNature Communications, 2023
M1 macrophages enter a glycolytic state when endogenous nitric oxide (NO) reprograms mitochondrial metabolism by limiting aconitase 2 and pyruvate dehydrogenase (PDH) activity. Here, we provide evidence that NO targets the PDH complex by using lipoate to
Erika M. Palmieri   +11 more
doaj   +1 more source

Structural Aspects and Characterization of Structure in the Processing of Titanium Grade4 Different Chips

open access: yesMetals, 2021
This study presents the structural aspects of the solid-state processing of various titanium chips. The structural characterization of: (1) commercial pure Ti in the as-received state, (2) manufactured chips, and (3) products of the chip processing are ...
Krzysztof Topolski   +2 more
doaj   +1 more source

Intelligent Protein Design and Molecular Characterization Techniques: A Comprehensive Review

open access: yesMolecules, 2023
In recent years, the widespread application of artificial intelligence algorithms in protein structure, function prediction, and de novo protein design has significantly accelerated the process of intelligent protein design and led to many noteworthy ...
Jingjing Wang   +5 more
doaj   +1 more source

Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10

open access: yesNature Communications, 2020
Human ubiquitin E3 ligase E6AP contains a Zn-binding AZUL domain. Here the authors identify and name RAZUL, a domain in proteasome substrate receptor hRpn10 that binds AZUL, recruiting E6AP to proteasomes, and they present the NMR structure of the RAZUL ...
Gwen R. Buel   +10 more
doaj   +1 more source

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