Structural constraints and dynamics of bacterial cell wall architecture [PDF]
Frontiers in Microbiology, 2015 The peptidoglycan wall (PG) is a unique structure which confers physical strength and defined shape to bacteria. It consists of a net-like macromolecule of peptide interlinked glycan chains overlying the cell membrane.
Miguel Angel De Pedro, Felipe eCava
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Immediate sensitivity to structural constraints in pronoun resolution [PDF]
Frontiers in Psychology, 2014 Real-time interpretation of pronouns is sometimes sensitive to the presence of grammatically-illicit antecedents, and sometimes not. This occasional sensitivity has been taken as evidence that structural constraints do not immediately impact the initial ...
Wing Yee eChow +5 more
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Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers [PDF]
Cell Reports, 2015 A highly glycosylated, trimeric envelope glycoprotein (Env) mediates HIV-1 cell entry. The high density and heterogeneity of the glycans shield Env from recognition by the immune system, but paradoxically, many potent broadly neutralizing antibodies ...
Laura K. Pritchard +13 more
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Improving object detection quality with structural constraints. [PDF]
PLoS ONE, 2022 Recent researches revealed object detection networks using the simple "classification loss + localization loss" training objective are not effectively optimized in many cases, while providing additional constraints on network features could effectively ...
Zihao Rong +3 more
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Deep learning extends de novo protein modelling coverage of genomes using iteratively predicted structural constraints. [PDF]
Nat Commun, 2019 The inapplicability of amino acid covariation methods to small protein families has limited their use for structural annotation of whole genomes. Recently, deep learning has shown promise in allowing accurate residue-residue contact prediction even for ...
Greener JG, Kandathil SM, Jones DT.
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The potential for structural errors in emergent constraints [PDF]
Earth System Dynamics, 2021 Studies of emergent constraints have frequently proposed that a single metric can constrain future responses of the Earth system to anthropogenic emissions.
B. M. Sanderson +9 more
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Subtype-specific structural constraints in the evolution of influenza A virus hemagglutinin genes. [PDF]
Sci Rep, 2016 The influenza A virus genome consists of eight RNA segments. RNA structures within these segments and complementary (cRNA) and protein-coding mRNAs may play a role in virus replication.
Gultyaev AP +5 more
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Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens. [PDF]
mSphere, 2016 Human norovirus interacts with the polymorphic human histo-blood group antigens (HBGAs), and this interaction is thought to be important for infection. The genogroup II genotype 4 (GII.4) noroviruses are the dominant cluster, evolve every other year, and
Singh BK, Leuthold MM, Hansman GS.
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Parallel computation of genome-scale RNA secondary structure to detect structural constraints on human genome. [PDF]
BMC Bioinformatics, 2016 RNA secondary structure around splice sites is known to assist normal splicing by promoting spliceosome recognition. However, analyzing the structural properties of entire intronic regions or pre-mRNA sequences has been difficult hitherto, owing to ...
Kawaguchi R, Kiryu H.
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Reconstruction of ancestral RNA sequences under multiple structural constraints [PDF]
BMC Genomics, 2016 Background Secondary structures form the scaffold of multiple sequence alignment of non-coding RNA (ncRNA) families. An accurate reconstruction of ancestral ncRNAs must use this structural signal.
Olivier Tremblay-Savard +2 more
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