Results 41 to 50 of about 1,527,783 (278)
Uncertainty in Crowd Data Sourcing under Structural Constraints [PDF]
, 2014 Applications extracting data from crowdsourcing platforms must deal with the uncertainty of crowd answers in two different ways: first, by deriving estimates of the correct value from the answers; second, by choosing crowd questions whose answers are ...
A Parameswaran +3 more
core +1 more source
Exponential Family Matrix Completion under Structural Constraints [PDF]
, 2015 We consider the matrix completion problem of recovering a structured matrix from noisy and partial measurements. Recent works have proposed tractable estimators with strong statistical guarantees for the case where the underlying matrix is low--rank, and
Ghosh, Joydeep +2 more
core
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Structural constraints identified with covariation analysis in ribosomal RNA. [PDF]
PLoS ONE, 2012 Covariation analysis is used to identify those positions with similar patterns of sequence variation in an alignment of RNA sequences. These constraints on the evolution of two positions are usually associated with a base pair in a helix.
Lei Shang +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Local Modal Frequency Improvement with Optimal Stiffener by Constraints Transformation Method
Applied Sciences, 2021 Local modal vibration could adversely affect the dynamical environment, which should be considered in the structural design. For the mode switching phenomena, the traditional structural optimization method for problems with specific order of modal ...
Shenyan Chen +4 more
doaj +1 more source
Strong Stationarity Conditions for Optimal Control of Hybrid Systems
, 2016 We present necessary and sufficient optimality conditions for finite time optimal control problems for a class of hybrid systems described by linear complementarity models.
Goulart, Paul +2 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Model selection in regression under structural constraints
, 2013 The paper considers model selection in regression under the additional structural constraints on admissible models where the number of potential predictors might be even larger than the available sample size.
Abramovich, Felix, Grinshtein, Vadim
core +1 more source