Results 81 to 90 of about 6,691,628 (330)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

STRUCTURALLY CONSTRAINED ROBUST OPTIMAL CONTROL CONTROL ÓPTIMO ROBUSTO CON RESTRICCIONES ESTRUCTURALES

Ingeniare: Revista Chilena de Ingeniería, 2006
A solution to the robust optimal control problem, subject to local states constraints in the feedback law, is presented. Examples with matched and unmatched uncertainty in the system matrix are presented.
Héctor Peña M, Sergio Mora C
doaj  

Empirical validation of ProteinMPNN’s efficiency in enhancing protein fitness

Frontiers in Genetics
Introduction: Protein engineering, which aims to improve the properties and functions of proteins, holds great research significance and application value.
Tianshu Wang, Tianshu Wang, Tianshu Wang, Tianshu Wang, Xiaocheng Jin, Xiaocheng Jin, Xiaocheng Jin, Xiaocheng Jin, Xiaoli Lu, Xiaoping Min, Xiaoping Min, Xiaoping Min, Xiaoping Min, Shengxiang Ge, Shengxiang Ge, Shengxiang Ge, Shengxiang Ge, Shaowei Li, Shaowei Li, Shaowei Li, Shaowei Li   +20 more
doaj   +1 more source

Explaining Influences on Career \u27Choice\u27 in Comparative Perspective [PDF]

, 2004
This study explores the influences on career choices of the MBA students from three countries at micro-individual, meso-institutional and relational and macro-structural levels, questioning the apparent dominance of ‘free choice’ in the context of ...
Erdogmus, Nihat, Kusku, Fatma, Ozbilgin, Mustafa   +2 more
core   +1 more source

Comparative analysis of rigidity across protein families [PDF]

, 2008
We present a comparative study in which 'pebble game' rigidity analysis is applied to multiple protein crystal structures, for each of six different protein families.
Case D A, DeLano W, Hespenheide B M, J E Jimenez-Roldan, Macchiarulo A, Mamonova T, R A Römer, S A Wells, Wells S A   +8 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Curvature constraints from large scale structure [PDF]

Journal of Cosmology and Astroparticle Physics, 2016
We modified the CLASS code in order to include relativistic galaxy number counts in spatially curved geometries; we present the formalism and study the effect of relativistic corrections on spatial curvature. The new version of the code is now publicly available.
Dio E. D., Montanari F., Raccanelli A., Durrer R., Kamionkowski M., Lesgourgues J.   +5 more
openaire   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

GERMANY’S LABOUR SHORTAGE: BETWEEN STRUCTURAL PRESSURE AND UNCERTAIN HORIZONS [PDF]

Global Economic Observer
Germany is currently facing a profound labour shortage that transcends sectoral boundaries and reflects deeper demographic and structural transformations. Following a brief post-pandemic rebound, the German economy has entered a phase of stagnation and
ANA-CRISTINA BÂLGĂR
doaj