Results 91 to 100 of about 4,022,588 (277)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Abstract of: On Cavitation in Transparent Structural Silicone Adhesive: TSSA

Challenging Glass Conference Proceedings, 2018
Cavitation in rubber-like materials describes sudden void growth of an initially voided material under hydrostatic tension until the material fails. To study the cavitation effect numerically, classical cavitation criteria are coupled with a continuum ...
Michael Drass, Vladimir A. Kolupaev, Jens Schneider, Stefan Kolling   +3 more
doaj   +1 more source

Materials data handbooks prepared for aluminum alloys 2014, 2219, and 5456, and stainless steel alloy 301 [PDF]

, 1967
Materials data handbooks summarize all presently known properties of commercially available structural aluminum alloys 2014, 2219, and 5456 and structural stainless steel alloy 301.

core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Screw pull-out force predictions in porcine radii using efficient nonlinear µFE models including contact and pre-damage

Frontiers in Bioengineering and Biotechnology
Nonlinear micro finite element (µFE) models have become the gold-standard for accurate numerical modeling of bone-screw systems. However, the detailed representation of bone microstructure, along with the inclusion of nonlinear material and contact, and ...
Pia Stefanek, J. D. Silva-Henao, J. D. Silva-Henao, Victoria Fiedler, A. G. Reisinger, A. G. Reisinger, Dieter H. Pahr, Alexander Synek   +7 more
doaj   +1 more source

Approximation methods for combined thermal/structural design [PDF]

Two approximation concepts for combined thermal/structural design are evaluated. The first concept is an approximate thermal analysis based on the first derivatives of structural temperatures with respect to design variables.
Haftka, R. T., Shore, C. P.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

ASTROS: A multidisciplinary automated structural design tool [PDF]

ASTROS (Automated Structural Optimization System) is a finite-element-based multidisciplinary structural optimization procedure developed under Air Force sponsorship to perform automated preliminary structural design. The design task is the determination
Neill, D. J.
core   +1 more source

Planning, creating and documenting a NASTRAN finite element model of a modern helicopter [PDF]

, 1985
Mathematical models based on the finite element method of structural analysis as embodied in the NASTRAN computer code are widely used by the helicopter industry to calculate static internal loads and vibration of airframe structure.
Gabal, R., Kesack, W., Reed, D., Ricks, R.   +3 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source