Results 81 to 90 of about 2,823,698 (212)

Simplified design procedures for fiber composite structural components/joints [PDF]

open access: yes
Simplified step-by-step design procedures are summarized, which are suitable for the preliminary design of composite structural components such as panels (laminates) and composite built-up structures (box beams).
Chamis, Christos C., Murthy, P. L. N.
core   +1 more source

The medieval ‘scientia' of structures: the rules of Rodrigo Gil de Hontañón [PDF]

open access: yes, 2002
Medieval builders didn't have a scientific structural theory, however gothic cathedrals were not build without a theory. Gothic masters had a ‘scientia', a body of knowledge which permitted the safe design of their buildings.
Huerta Fernández, Santiago
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Methods for structural design at elevated temperatures [PDF]

open access: yes
A procedure which can be used to design elevated temperature structures is discussed. The desired goal is to have the same confidence in the structural integrity at elevated temperature as the factor of safety gives on mechanical loads at room ...
Ellison, A. M.   +2 more
core   +1 more source

Design of single storey curved spatial building [PDF]

open access: yes, 2019
Tato bakalářská práce se zabívá návrhovou studií a statickou analýzou sřešní konstrukce s použitím obloukových prolamovaných nosníků. Struktura má rozměry 30 m x 30 m, je lokalizovaná v Liberci, a stojí na čtyřech sloupech.
Jean Philippe Cam
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Advanced aeroservoelastic stabilization techniques for hypersonic flight vehicles [PDF]

open access: yes
Advanced high performance vehicles, including Single-Stage-To-Orbit (SSTO) hypersonic flight vehicles, that are statically unstable, require higher bandwidth flight control systems to compensate for the instability resulting in interactions between the ...
Chan, Samuel Y.   +5 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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