Results 91 to 100 of about 13,517,481 (303)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Research by design: interdisciplinary explorations within architectural design, structural design and material lab to develop innovative bio-based material pavilions

open access: yes, 2019
The Netherlands are at the forefront of an ambitious agenda: to make the building industry fully circular by 2050. In this context this interdisciplinary ‘research by design’ master project explored, tested and experimented with bio-based composite ...
Schröder, Torsten   +6 more
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Toolpath-Driven Surface Articulation for Wax Formwork Technology in the Production of Thin-Shell, Robotic, CO2-Reduced Shotcrete Elements

open access: yesBuildings
This study introduces a digital fabrication process for producing recyclable, closed-loop wax formwork for architectural concrete applications with visually rich surface articulation while drastically reducing formwork milling time.
Sven Jonischkies   +6 more
doaj   +1 more source

Energy supply for the building stock of tomorrow – A case study [PDF]

open access: yesE3S Web of Conferences
Reducing energy consumption and using renewable energy sources for the building operation is crucial to achieve lower overall greenhouse gas (GHG) emissions.
Reidelbach Franka   +3 more
doaj   +1 more source

Bio-Based Composite Footbridge: Design, Production and In Situ Monitoring [PDF]

open access: yes, 2019
This paper deals with the design, production and monitoring of a bio-composite footbridge with a span of 14 m across the river Dommel in the city of Eindhoven, the Netherlands.
Blok, Rijk (author)   +9 more
core   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Resource-efficient structural design [PDF]

open access: yes, 2018
The building and construction industry is by far the most resource intensive sector in the European Union [1] and the numbers worldwide are comparable. This sector, which is based on a very strong responsibility of architects as well structural engineers
Blok, R.   +5 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

GS&E journal > Double ring bending tests on heat pretreated soda–lime silicate glass

open access: yesChallenging Glass Conference Proceedings, 2020
The strength of glass plays an important role in the dimensioning of glass components in the building industry. Here, not only parameters such as support conditions, loading rate, relative humidity etc.
Gregor Schwind   +3 more
doaj  

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