Results 91 to 100 of about 13,517,481 (303)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Netherlands are at the forefront of an ambitious agenda: to make the building industry fully circular by 2050. In this context this interdisciplinary ‘research by design’ master project explored, tested and experimented with bio-based composite ...
Schröder, Torsten +6 more
core
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
This study introduces a digital fabrication process for producing recyclable, closed-loop wax formwork for architectural concrete applications with visually rich surface articulation while drastically reducing formwork milling time.
Sven Jonischkies +6 more
doaj +1 more source
Energy supply for the building stock of tomorrow – A case study [PDF]
Reducing energy consumption and using renewable energy sources for the building operation is crucial to achieve lower overall greenhouse gas (GHG) emissions.
Reidelbach Franka +3 more
doaj +1 more source
Bio-Based Composite Footbridge: Design, Production and In Situ Monitoring [PDF]
This paper deals with the design, production and monitoring of a bio-composite footbridge with a span of 14 m across the river Dommel in the city of Eindhoven, the Netherlands.
Blok, Rijk (author) +9 more
core +3 more sources
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Resource-efficient structural design [PDF]
The building and construction industry is by far the most resource intensive sector in the European Union [1] and the numbers worldwide are comparable. This sector, which is based on a very strong responsibility of architects as well structural engineers
Blok, R. +5 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
GS&E journal > Double ring bending tests on heat pretreated soda–lime silicate glass
The strength of glass plays an important role in the dimensioning of glass components in the building industry. Here, not only parameters such as support conditions, loading rate, relative humidity etc.
Gregor Schwind +3 more
doaj

