Results 51 to 60 of about 4,034,259 (329)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Space shuttle orbiter leading-edge flight performance compared to design goals [PDF]
, 1983 Thermo-structural performance of the Space Shuttle orbiter Columbia's leading-edge structural subsystem for the first five (5) flights is compared with the design goals.
Curry, D. M. +2 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Fabrication of Dry Connection Through Stamping and Milling of Green-State Concrete
BuildingsThis study addresses the fabrication challenges associated with producing diverse geometries for concrete dry connections, particularly regarding cost, time, and geometric limitations. The research investigates methods for fabricating precise, rebar-free
Abtin Baghdadi +3 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Sensors, 2020 Structural health monitoring (SHM) is the continuous on-board monitoring of a structure’s condition during operation by integrated systems of sensors.
Christoph Kralovec, Martin Schagerl
doaj +1 more source
Bayesian Markov Chain Monte Carlo inversion of surface-based transient electromagnetic data
SN Applied Sciences, 2022 Article Highlights 1. We propose a Bayesian MCMC procedure for surface-based TEM data inversion and apply it successfully both in synthetic data and field data. 2.
Shengqiang Deng +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Study on development technology of aircraft smart cockpit
Hangkong gongcheng jinzhanIt is clear that the smart development of the aircraft cockpit is inevitable，and the study on the development technology of aircraft smart cockpit can provide the reference support for future aircraft smart cockpit design.
LIU Guanghui, SUN Di, LI Yuanyuan
doaj +1 more source
Highly efficient semi‐active oil damper with energy recovery system
Japan Architectural Review, 2019 This paper presents a novel semi‐active oil damper developed to overcome the limitations of existing oil dampers by introducing a unique energy recovery system.
Ryusuke Fukuda, Haruhiko Kurino
doaj +1 more source