Results 31 to 40 of about 3,458,614 (298)

Anti-Candidal Marine Natural Products: A Review

open access: yesJournal of Fungi, 2023
Candida spp. are common opportunistic microorganisms in the human body and can cause mucosal, cutaneous, and systemic infections, mainly in individuals with weakened immune systems.
Arumugam Ganeshkumar   +3 more
doaj   +1 more source

Development of decision-making competence in courses of spectrometric analysis of organic compounds

open access: yesEducación Química, 2018
The aim of the present study was to develop a level of competence that is not normally found in graduate or post-graduate chemistry courses, through a didactic intervention in the discipline of spectrometric analysis of organic compounds.
Ricardo Oliveira Silva   +6 more
doaj   +1 more source

Discovery of Brominated Alboflavusins With Anti-MRSA Activities

open access: yesFrontiers in Microbiology, 2021
As methicillin-resistant Staphylococcus aureus (MRSA) is becoming a serious pathogenic threaten to human health worldwide, there is an urgent need to discover new antibiotics for the treatment of MRSA infections.
Chao Li   +8 more
doaj   +1 more source

NeuroCarb : artificial neural networks for NMR structure elucidation of oligosaccharides [PDF]

open access: yes, 2006
Recombinant proteins and monoclonal antibodies offer great promise as therapeutics for hundreds of diseases. Today, there are almost 400 biotechnology drugs in development for over 200 different conditions.
Studer-Imwinkelried, Matthias
core   +1 more source

Structure elucidation of the water-soluble organic carbon fraction in atmospheric aerosols by mass spectrometry [PDF]

open access: yes, 2006
Atmospheric aerosols can act as cloud condensation nuclei (CCN) and scatter or absorb light thus influencing many important processes in the atmosphere.
Romero, Fernando
core   +1 more source

Terpene Glycosides from Sanguisorba officinalis and Their Anti-Inflammatory Effects

open access: yesMolecules, 2019
Two new terpene glycosides (1−2) along with two known analogs (3−4) were obtained from the root of Sanguisorba officinalis, which is a common traditional Chinese medicine (TCM).
Da-Le Guo   +9 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Brief Review on Fungal Endophytes

open access: yesInternational Journal of Secondary Metabolite, 2018
Fungal endophytes are the critical organisms in the environment residing in the plant tissues without showing any harmful effects on its host life cycle.
Rohit Shankar Mane   +2 more
doaj   +1 more source

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