Results 31 to 40 of about 3,458,614 (298)
Anti-Candidal Marine Natural Products: A Review
Candida spp. are common opportunistic microorganisms in the human body and can cause mucosal, cutaneous, and systemic infections, mainly in individuals with weakened immune systems.
Arumugam Ganeshkumar +3 more
doaj +1 more source
Development of decision-making competence in courses of spectrometric analysis of organic compounds
The aim of the present study was to develop a level of competence that is not normally found in graduate or post-graduate chemistry courses, through a didactic intervention in the discipline of spectrometric analysis of organic compounds.
Ricardo Oliveira Silva +6 more
doaj +1 more source
Discovery of Brominated Alboflavusins With Anti-MRSA Activities
As methicillin-resistant Staphylococcus aureus (MRSA) is becoming a serious pathogenic threaten to human health worldwide, there is an urgent need to discover new antibiotics for the treatment of MRSA infections.
Chao Li +8 more
doaj +1 more source
NeuroCarb : artificial neural networks for NMR structure elucidation of oligosaccharides [PDF]
Recombinant proteins and monoclonal antibodies offer great promise as therapeutics for hundreds of diseases. Today, there are almost 400 biotechnology drugs in development for over 200 different conditions.
Studer-Imwinkelried, Matthias
core +1 more source
Structure elucidation of the water-soluble organic carbon fraction in atmospheric aerosols by mass spectrometry [PDF]
Atmospheric aerosols can act as cloud condensation nuclei (CCN) and scatter or absorb light thus influencing many important processes in the atmosphere.
Romero, Fernando
core +1 more source
Terpene Glycosides from Sanguisorba officinalis and Their Anti-Inflammatory Effects
Two new terpene glycosides (1−2) along with two known analogs (3−4) were obtained from the root of Sanguisorba officinalis, which is a common traditional Chinese medicine (TCM).
Da-Le Guo +9 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Brief Review on Fungal Endophytes
Fungal endophytes are the critical organisms in the environment residing in the plant tissues without showing any harmful effects on its host life cycle.
Rohit Shankar Mane +2 more
doaj +1 more source

