A novel six3 mutation segregates with holoprosencephaly in a large family [PDF]
Holoprosencephaly is the most common structural malformation of the forebrain in humans and has a complex etiology including chromosomal aberrations, single gene mutations and environmental components.
Abecasis +40 more
core +1 more source
Structural characterization of phytotoxic terpenoids from Cestrum parqui. [PDF]
Isolation, chemical characterization and phytotoxicity of nine polyhydroxylated terpenes (five C13 nor-isoprenoids, two sesquiterpenes, a spirostane and a pseudosapogenin) from Cestrum parqui LHerr are reported.
D'Abrosca, B +6 more
core +1 more source
Development of decision-making competence in courses of spectrometric analysis of organic compounds
The aim of the present study was to develop a level of competence that is not normally found in graduate or post-graduate chemistry courses, through a didactic intervention in the discipline of spectrometric analysis of organic compounds.
Ricardo Oliveira Silva +6 more
doaj +1 more source
Strain prioritization and genome mining for enediyne natural products [PDF]
The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date.
Ben Shen +18 more
core +2 more sources
Anti-Candidal Marine Natural Products: A Review
Candida spp. are common opportunistic microorganisms in the human body and can cause mucosal, cutaneous, and systemic infections, mainly in individuals with weakened immune systems.
Arumugam Ganeshkumar +3 more
doaj +1 more source
Optical Spectra of p-Doped PEDOT Nano-Aggregates Provide Insight into the Material Disorder
Highly doped Poly(3,4-ethylenedioxythiophene) or PEDOT is a conductive polymer with a wide range of applications in energy conversion due to its ease of processing, optical properties and high conductivity.
Aspuru-Guzik, Alán +3 more
core +3 more sources
Purification and structure elucidation of three naturally bioactive molecules from the new terrestrial Streptomyces sp. TN17 strain [PDF]
Thirty litres of fermentation broth was extracted from the newly isolated Streptomyces sp. strain TN17 and various separation and purification steps led to the isolation of three pure bioactive compounds (1–3).
Coppel, Yannick +5 more
core +2 more sources
Discovery of Brominated Alboflavusins With Anti-MRSA Activities
As methicillin-resistant Staphylococcus aureus (MRSA) is becoming a serious pathogenic threaten to human health worldwide, there is an urgent need to discover new antibiotics for the treatment of MRSA infections.
Chao Li +8 more
doaj +1 more source
A new acylated and triterpenoidal saponin, named GS1, was isolated from the roots of Gypsophila arrostii Guss. On the basis of acid hydrolysis, comprehensive spectroscopic analyses and comparison with spectral data of known compounds, its structure was ...
Arslan, I
core +2 more sources
Terpene Glycosides from Sanguisorba officinalis and Their Anti-Inflammatory Effects
Two new terpene glycosides (1−2) along with two known analogs (3−4) were obtained from the root of Sanguisorba officinalis, which is a common traditional Chinese medicine (TCM).
Da-Le Guo +9 more
doaj +1 more source

