Results 141 to 150 of about 622,519 (292)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Structural Engineering of Layered Nanomaterials for Biomedical Applications. [PDF]

Chem Rev
Hu T, Yang Y, Wang T, Ge M, Yu C, Zha J, Pan X, Zhou Z, Ma L, Liang R, Tan C.   +10 more
europepmc   +1 more source

Recent Advancement and Structural Engineering in Transition Metal Dichalcogenides for Alkali Metal Ions Batteries. [PDF]

Materials (Basel), 2023
Ullah N, Guziejewski D, Yuan A, Shah SA.
europepmc   +1 more source

Human-in-the-Loop Digital Twins for Urban Infrastructure Decision-Making: Integrating Engineering Judgment with Structural Health Monitoring in Tehran

Maryam Rahimi
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Structural engineering of silver nanoparticles for enhanced photoacoustic imaging. [PDF]

Nanoscale Adv
Zhang R, Dias M, Li Y, Rütten S, Kiessling F, Lammers T, Pallares RM.   +6 more
europepmc   +1 more source

Structural engineering from an inverse problems perspective. [PDF]

Proc Math Phys Eng Sci, 2022
Gallet A, Rigby S, Tallman TN, Kong X, Hajirasouliha I, Liew A, Liu D, Chen L, Hauptmann A, Smyl D.   +9 more
europepmc   +1 more source

Evolution Law of Structural Form and Heat Transfer Performance of Thermal Insulation System: Numerical Calculation, Experimental Study and Engineering Application

, 2022
Yang Ding, Shuang-xi Zhou, Kai Cao, Jing-liang DONG, Zhong-ping WANG   +4 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Boosting AMPs' Power: From Structural Engineering to Nanotechnology-Based Delivery. [PDF]

Molecules
Ajayi OE, Bellavita R, Imbò LE, Palladino S, Braccia S, Falanga A, Galdiero S.   +6 more
europepmc   +1 more source