Results 31 to 40 of about 568,488 (296)

Periodic Layout Optimization of Cyclic Symmetric Structure

open access: yesIEEE Access, 2019
This paper proposes a new optimization method to solve periodic layout optimization of a cyclic symmetric structure by means of the guide-weight method.
Hong-Yu Jiao, Ying Li, Lan-Yu Yang
doaj   +1 more source

Sensitivity Analysis of the Global Response of Flexible Rockfall Barriers

open access: yesGeosciences, 2022
Protection barriers against the fall of boulders and rocks are structures with non-linear mechanical behaviour that make the study particularly complex.
Cyril Douthe   +2 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes

open access: yesFrontiers in Immunology
IntroductionDiabetes mellitus (DM) is recognized as one of the oldest chronic diseases and has become a significant public health issue, necessitating innovative therapeutic strategies to enhance patient outcomes.
Abbas Khan   +3 more
doaj   +1 more source

Vulnerability and Robustness of Civil Infrastructure Systems to Hurricanes

open access: yesFrontiers in Built Environment, 2017
Civil infrastructure systems play an important role in community resilience. Without proper functioning of the infrastructure, especially power delivery, society will not recover quickly from disruptive events, such as hurricanes.
Shuoqi Wang, Dorothy A. Reed
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Systematic Mapping of Circular Economy in Structural Engineering

open access: yesBuildings
Facing increasing sustainability demands, the construction industry is at a turning point where the implementation of circular economy (CE) strategies plays an essential role in driving the necessary transformation aimed at reducing the environmental ...
Hanne Rangnes Seeberg   +2 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Building Information Modelling in Structural Engineering: A Qualitative Literature Review

open access: yesCivilEng, 2021
Over the past decade, the fields of civil engineering, i.e., structural engineering, have increasingly used the building information modelling (BIM) approach in both professional practice and as the focus of research.
Vittoria Ciotta   +3 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

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