Results 41 to 50 of about 8,308,567 (300)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Contribution to probabilistic modeling of soil geo-mechanical properties for structural reliability analysis of buried pipes and foundations

open access: yesJournal of Materials and Engineering Structures, 2019
This present study synthesizes a numerical approach to optimize foundation systems design and underground pipes based on the combination of elastoplastic soil behavior and probabilistic modeling of its geo-mechanical characteristics.
Nabil KAZI TANI   +3 more
doaj  

Materials and Structures Used in Aeronautics: Present and Future Perspectives [PDF]

open access: yesINCAS Bulletin
In recent years, significant advancements have been made in the development of novel materials for aeronautic applications. This effort aims to reduce costs by extending the operational life of structural and engine components, improving fuel economy ...
Mihai FLOREA   +5 more
doaj   +1 more source

Synergy between structural and architectural engineering: the point of view of the structural engineer [PDF]

open access: yesWIT Transactions on The Built Environment, 2014
Two departments of Vrije Universiteit Brussels (VUB), being the Department of Architectural Engineering (ARCH) and the Department of Mechanics of Materials and Constructions (MeMC), both in the Faculty of Engineering, are both scientifically active in various aspects of structural and architectural engineering.
Pyl, Lincy   +4 more
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

DUCTILITY AND STRENGTH OF REINFORCED CONCRETE BEAMS INTRINSICALLY REINFORCED WITH POLYPROPYLENE FIBRES [PDF]

open access: yes, 2013
The Thirteenth East Asia-Pacific Conference on Structural Engineering and Construction (EASEC-13), September 11-13, 2013, Sapporo ...
GHOSNI, N.   +8 more
core  

Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes

open access: yesFrontiers in Immunology
IntroductionDiabetes mellitus (DM) is recognized as one of the oldest chronic diseases and has become a significant public health issue, necessitating innovative therapeutic strategies to enhance patient outcomes.
Abbas Khan   +3 more
doaj   +1 more source

Artificial Intelligence-Based Design and Analysis of Passive Control Structures: An Overview [PDF]

open access: yesJournal of Soft Computing in Civil Engineering
Recently, artificial intelligence (AI) has been widely adopted in the design and analysis of passively controlled structures. This study provides a comprehensive overview of AI-based methodologies aimed at enhancing the resilience and efficiency of ...
Ausamah AL Houri   +2 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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