Results 61 to 70 of about 8,308,567 (300)
E-Learning, the future of structural engineering education?
, 2015 In last years, the traditional blackboard teaching has been supplemented by visual aids like slide projectors and videos. The phenomenal growth of the Internet has brought in new teaching media, such as E-learning.
Lozano Galant, José Antonio +11 more
core +1 more source
The structural reliability of bridges subject to time-dependent deterioration [PDF]
, 2007 Paper presented at the 11th International Conference on Civil, Structural and Environmental Engineering Computing, Malta, 18-21 September 2007The reliability of the structural performance of any given structure is affected by both in-service loading and ...
Bordallo-Ruiz, A. +10 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Future trends in railway engineering [PDF]
, 2009 This article reviews the current state of railway engineering with a focus on the steady development of conventional technology that has led to the 575 km/h run of the French TGV train in 2007.
Iwnicki, Simon D., Iwnicki, S.
core +1 more source
ComputationHorizontally curved steel I-beams exhibit a complicated mechanical response as they experience a combination of bending, shear, and torsion, which varies based on the geometry of the beam at hand. The behaviour of these beams is therefore quite difficult
Elvis Ababu +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Preface [to the 2005 Australian Structural Engineering Conference (ASEC) issue of Australian Journal of Structural Engineering] [PDF]
, 2007 Preface to Australian Journal of Structural Engineering Vol.
Uy, Brian, Liang, Qing Quan
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source