Results 61 to 70 of about 671,923 (262)

Verrouillage professionnel

Revue d'anthropologie des connaissances, 2014
Recent challenges such as sustainable development and climate change suggest engineers to focus on societal issues. However, as this case study of structural design shows, professional arrangements within the construction field constrain engineers ...
Andrew Chilvers, Sarah Bell
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Engineering Bulk Photovoltaic Effect in 2D Transition Metal Dichalcogenides

Advanced Science
A promising method for producing photocurrents above the Shockley–Queisser limit in non‐centrosymmetric materials is the bulk photovoltaic effect (BPVE), especially in low‐dimensional materials.
Sikandar Aftab, Arden L. Moore
doaj   +1 more source

Composite Mechanics for Engine Structures [PDF]

Volume 5: Manufacturing Materials and Metallurgy; Ceramics; Structures and Dynamics; Controls, Diagnostics and Instrumentation; Process Industries; General, 1987
Recent research activities/accomplishments at Lewis Research Center on composite mechanics for engine structures are reviewed in summary form. The activities mainly focused on developing procedures for the computational simulation of composite intrinsic and structural behavior. The computational simulation encompasses all aspects of composite mechanics,
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Study on energy conservation and carbon emission reduction design of timber structure building

The Journal of Engineering, 2019
Replacing traditional building materials with renewable and sustainable materials such as timber can control environmental pollution such as energy consumption and carbon emission in the whole life cycle of a building, which is conducive to energy ...
Miao Yue, Wenxian Li, Xinling Cheng, Yujie Chen, Liu Xu, Yanshuai Shi   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Deflection characterisation of rotary systems using ground-based radar

The Journal of Engineering, 2019
In the last two decades, an increase in large rotary machines/systems has been witnessed. To ensure safe operation of these systems especially due to extreme stress caused by centrifugal forces as well as the wind or water loadings, regular structural ...
Francis X. Ochieng, Haoyang Jiang, Craig M. Hancock, Gethin W. Roberts, Julien Le Kernec, Xu Tang, Huib de Ligt   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Periodic Layout Optimization of Cyclic Symmetric Structure

IEEE Access, 2019
This paper proposes a new optimization method to solve periodic layout optimization of a cyclic symmetric structure by means of the guide-weight method.
Hong-Yu Jiao, Ying Li, Lan-Yu Yang
doaj   +1 more source