Results 91 to 100 of about 1,885,843 (350)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Advanced Numerical Simulation of Scour around Bridge Piers: Effects of Pier Geometry and Debris on Scour Depth

Journal of Marine Science and Engineering
Investigating different pier shapes and debris Finteractions in scour patterns is vital for understanding the risks to bridge stability. This study investigates the impact of different shapes of pier and debris interactions on scour patterns using ...
Muhanad Al-Jubouri, Richard P. Ray, Ethar H. Abbas   +2 more
doaj   +1 more source

Evolution of Persian traditional architecture through the history

Journal of Architecture and Urbanism, 2015
The architecture of Iran is wholly based on the comprehensive use of knowledge of both metaphysical and physical sciences. Architecture and structural engineering in Iran involve a great range of buildings distributed over a vast area from the borders of
Mehrdad Hejazi, Bina Hejazi, Saba Hejazi
doaj   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

FEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian, Di Liu, Bing Liu, Yu Lan, Jie Zhou   +4 more
wiley   +1 more source

Diffusion geometry unravels the emergence of functional clusters in collective phenomena

, 2017
Collective phenomena emerge from the interaction of natural or artificial units with a complex organization. The interplay between structural patterns and dynamics might induce functional clusters that, in general, are different from topological ones. In
De Domenico, Manlio
core   +1 more source

Prediction of Scour Depth for Diverse Pier Shapes Utilizing Two-Dimensional Hydraulic Engineering Center’s River Analysis System Sediment Model

Fluids
Examining scouring around bridge piers is crucial for ensuring water-related infrastructure’s long-term safety and stability. Accurate forecasting models are essential for addressing scour, especially in complex water systems where traditional methods ...
Muhanad Al-Jubouri, Richard P. Ray, Ethar H. Abbas   +2 more
doaj   +1 more source

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden, Charles Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren T. Evans, Frederick A. Schroeder, Jacob M. Hooker, Michel Koole, Janice E. Kranz, Tonya M. Gilbert, Philip Van Damme, Koen Van Laere   +15 more
wiley   +1 more source

A new finite element for generalized in-plane pipe loading. Experimental and numerical comparison [PDF]

, 2010
In structural engineering, the geometry of a large number of structural details may involve the combination of straight and curved parts in order to meet requirements of functionality and/or attractive design.
Fonseca, E.M.M., Melo, F.J.M.Q. de, Oliveira, C.A.M de, Piloto, P.A.G.   +3 more
core  

Multimodel structural performance monitoring [PDF]

, 2015
Journal ArticleMeasurements from load tests may lead to numerical models that better reflect structural behavior. This kind of system identification is not straightforward due to important uncertainties in measurement and models.
Goulet, James-A., Kripakaran, Prakash, Smith, Ian F.C.   +2 more
core   +1 more source

COMSOL Multiphysics GmbH

CHIMIA, 2023
COMSOL: Simulation Drives Understanding COMSOL Multiphysics® is a general-purpose simulation software used in all fields of engineering, manufacturing, and scientific research.
David Spichiger
doaj