Results 71 to 80 of about 1,612,198 (310)

Si3AlP: A new promising material for solar cell absorber

open access: yes, 2012
First-principles calculations are performed to study the structural and optoelectronic properties of the newly synthesized nonisovalent and lattice-matched (Si2)0.6(AlP)0.4 alloy [T. Watkins et al., J. Am. Chem. Soc.
Chen S.   +22 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Eminent Structural Engineer: David P. Billington (1927–2018). Inspiring Generations Through the Integration of Engineering and Art [PDF]

open access: yesStructural Engineering International, 2018
1927 – Born June 1, Bryn Mawr, PA1950 – Princeton University, BSE1951 – Married Phyllis Bergquist, with whom he had six children1950–1952 – Fulbright Fellowship, Leuven, Belgium, to study post-war ...
Ignacio Payá-Zaforteza   +1 more
openaire   +2 more sources

Bannan Engineering Laboratories Redesign [PDF]

open access: yes, 2014
Due to the growing student body within Santa Clara University\u27s School of Engineering, an increase in classrooms, laboratories, offices, and study spaces is needed to for student engineering resources.
Candelaria, Pia Johanna   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Prediction of Scour Depth for Diverse Pier Shapes Utilizing Two-Dimensional Hydraulic Engineering Center’s River Analysis System Sediment Model

open access: yesFluids
Examining scouring around bridge piers is crucial for ensuring water-related infrastructure’s long-term safety and stability. Accurate forecasting models are essential for addressing scour, especially in complex water systems where traditional methods ...
Muhanad Al-Jubouri   +2 more
doaj   +1 more source

General deep learning framework for emissivity engineering

open access: yesLight: Science & Applications, 2023
Wavelength-selective thermal emitters (WS-TEs) have been frequently designed to achieve desired target emissivity spectra, as a typical emissivity engineering, for broad applications such as thermal camouflage, radiative cooling, and gas sensing, etc ...
Shilv Yu   +8 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Advanced Numerical Simulation of Scour around Bridge Piers: Effects of Pier Geometry and Debris on Scour Depth

open access: yesJournal of Marine Science and Engineering
Investigating different pier shapes and debris Finteractions in scour patterns is vital for understanding the risks to bridge stability. This study investigates the impact of different shapes of pier and debris interactions on scour patterns using ...
Muhanad Al-Jubouri   +2 more
doaj   +1 more source

COMSOL: Simulation Drives Understanding

open access: yesCHIMIA, 2022
COMSOL Multiphysics® is a general-purpose simulation software used in all fields of engineering, manufacturing, and scientific research. The software offers fully coupled multiphysics and singlephysics modeling capabilities, simulation data management,
David Spichiger
doaj  

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