Results 71 to 80 of about 1,607,586 (321)

General deep learning framework for emissivity engineering

Light: Science & Applications, 2023
Wavelength-selective thermal emitters (WS-TEs) have been frequently designed to achieve desired target emissivity spectra, as a typical emissivity engineering, for broad applications such as thermal camouflage, radiative cooling, and gas sensing, etc ...
Shilv Yu, Peng Zhou, Wang Xi, Zihe Chen, Yuheng Deng, Xiaobing Luo, Wangnan Li, Junichiro Shiomi, Run Hu   +8 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Prediction of Scour Depth for Diverse Pier Shapes Utilizing Two-Dimensional Hydraulic Engineering Center’s River Analysis System Sediment Model

Fluids
Examining scouring around bridge piers is crucial for ensuring water-related infrastructure’s long-term safety and stability. Accurate forecasting models are essential for addressing scour, especially in complex water systems where traditional methods ...
Muhanad Al-Jubouri, Richard P. Ray, Ethar H. Abbas   +2 more
doaj   +1 more source

Eminent Structural Engineer: David P. Billington (1927–2018). Inspiring Generations Through the Integration of Engineering and Art [PDF]

Structural Engineering International, 2018
1927 – Born June 1, Bryn Mawr, PA1950 – Princeton University, BSE1951 – Married Phyllis Bergquist, with whom he had six children1950–1952 – Fulbright Fellowship, Leuven, Belgium, to study post-war ...
Ignacio Payá-Zaforteza, Maria E. Moreyra Garlock   +1 more
openaire   +2 more sources

Unravelling the functional biomechanics of dental features and tooth wear [PDF]

, 2013
Most of the morphological features recognized in hominin teeth, particularly the topography of the occlusal surface, are generally interpreted as an evolutionary functional adaptation for mechanical food processing.
Benazzi, Stefano, Hublin, Jean-Jacques, Kullmer, Ottmar, Nguyen, Huynh Nhu   +3 more
core   +3 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Advanced Numerical Simulation of Scour around Bridge Piers: Effects of Pier Geometry and Debris on Scour Depth

Journal of Marine Science and Engineering
Investigating different pier shapes and debris Finteractions in scour patterns is vital for understanding the risks to bridge stability. This study investigates the impact of different shapes of pier and debris interactions on scour patterns using ...
Muhanad Al-Jubouri, Richard P. Ray, Ethar H. Abbas   +2 more
doaj   +1 more source

COMSOL: Simulation Drives Understanding

CHIMIA, 2022
COMSOL Multiphysics® is a general-purpose simulation software used in all fields of engineering, manufacturing, and scientific research. The software offers fully coupled multiphysics and singlephysics modeling capabilities, simulation data management,
David Spichiger
doaj  

Study on Optimization Design of Reinforced Concrete Special-shaped Column Frame Structure

Chemical Engineering Transactions, 2017
In order to make the design of reinforced concrete (RC) special-shaped column frame structure safe and economical, the optimization design of the structure based on the general design is put forward.
Jingbo An
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source