Results 111 to 120 of about 35,892 (312)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Structural magnetic induction dampers in buildings [PDF]
, 2003 Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2003.Includes bibliographical references (leaf 49).This thesis discusses the feasibility of structural magnetic induction dampers for dampening ...
Augé, Laurent J. (Laurent Jacques), 1980-
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Stiffness optimization for wind-induced dynamic serviceability design of tall buildings
, 2009 Contemporary tall buildings with increasing height and slenderness are highly sensitive to the actions of wind. The structural design of modern tall buildings is generally governed by the need to provide adequate strength and stiffness against dynamic ...
Chan, C. M. +5 more
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
, 2012 The majority of existing reinforced concrete (RC) buildings were built prior to the introduction of seismic codes. As observed in various recent earthquakes, due to their lack of structural capacity and ductility such structures are very vulnerable and
Varum, H., Rossetto, T., Borg, R. C.
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Performance-based earthquake engineering necessitates the development of reliable nonlinear analysis models that are able to simulate the behavior of structures from the onset of damage through collapse. These models provide engineering demand parameters
Krawinkler, Helmut, Lignos, Dimitrios
core +1 more source
High-Performance Tall Buildings: An Overview of Recent Developments
EncyclopediaThe evolution of tall buildings has been shaped by distinct architectural styles, beginning around 1875 and progressing through various stylistic architectural movements.
Kheir Al-Kodmany, Mir M. Ali
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Mega-tall buildings: current trends, challenges and future prospects
Discover Civil EngineeringThis paper focuses on mega-tall buildings that are distinguished from other skyscrapers by their height, which is 600 m or more. The construction of mega-tall buildings is a twenty-first-century phenomenon, representing the pinnacle of modern building ...
Tanmoy Konar
doaj +1 more source