Results 101 to 110 of about 166,491,988 (249)

DUCTILITY AND STRENGTH OF REINFORCED CONCRETE BEAMS INTRINSICALLY REINFORCED WITH POLYPROPYLENE FIBRES [PDF]

open access: yes, 2013
The Thirteenth East Asia-Pacific Conference on Structural Engineering and Construction (EASEC-13), September 11-13, 2013, Sapporo ...
GHOSNI, N.   +8 more
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Mega-tall buildings: current trends, challenges and future prospects

open access: yesDiscover Civil Engineering
This paper focuses on mega-tall buildings that are distinguished from other skyscrapers by their height, which is 600 m or more. The construction of mega-tall buildings is a twenty-first-century phenomenon, representing the pinnacle of modern building ...
Tanmoy Konar
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

AN INTEGRATED BIM METHODOLOGY FOR THE SEISMIC ASSESSMENT OF MASONRY BUILDINGS

open access: yes, 2020
Building Information Modelling is one of the most innovative and promising technologies that are taking place in the construction industry. However, BIM implementation in structural engineering is not as common as in architectural design and this ...
B. Puccini   +3 more
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

High-Performance Tall Buildings: An Overview of Recent Developments

open access: yesEncyclopedia
The evolution of tall buildings has been shaped by distinct architectural styles, beginning around 1875 and progressing through various stylistic architectural movements.
Kheir Al-Kodmany, Mir M. Ali
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Phenomenological model for the damage diagnosis of masonry structures based on crack parameters

open access: yesBuilt Heritage
Assessment of the technical condition of historic buildings is a key task in ensuring their structural safety and long-term preservation, particularly in the presence of damage associated with crack formation.
Oksana Kichaieva, Dietmar Adam
doaj   +1 more source

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