Results 101 to 110 of about 35,892 (312)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

The behaviour of modern flexible framed structures undergoing differential settlement

open access: yes, 2010
Modern office buildings are often open plan buildings with a frame consisting of flat RC slabs, RC columns and non-load bearing internal and external partitions and facades.
Smit, Gerrit
core  

Development and validation of a generalised engineering methodology for thermal analysis of structural members in fire. [PDF]

open access: yes, 2007
A novel methodology for generalising CFD-based approaches for thermal analysis of protected steelwork in fire has been developed, known as GeniSTELA.
Liang, Hong   +6 more
core  

Effectiveness of High-Performance Concrete Jacketing in Improving the Performance of RC Structures

open access: yesApplied Sciences
The seismic vulnerability of existing reinforced concrete (RC) buildings that constitute a large portion of the urban building stock has become a growing concern for urban safety.
Marijana Hadzima-Nyarko   +6 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Passive Design of Buildings for Extreme Weather Environment [PDF]

open access: yes, 2013
Buildings account for nearly 40% of the end-use energy consumption and carbon emissions globally. Buildings, once built, are used at least for several decades.
S., Tokbolat   +2 more
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Materials and techniques of Art Nouveau architecture in Italy and Portugal: a first insight for an European route to consistent restoration

open access: yes, 2009
The results of the investigations on building materials and techniques of Casa Major Pessoa, a typical Art Nouveau construction in Aveiro (Portugal), and two coeval Art Nouveau buildings in Bologna (Italy) are presented as a methodological contribution
Sandrolini, F.   +7 more
core  

Historical background, current trends and future prospects of supertall buildings

open access: yesDiscover Civil Engineering
Skyscrapers having a height of 300 m or more, but less than 600 m, are designated as supertall buildings. The first supertall building was constructed in New York City in the year 1930.
Tanmoy Konar
doaj   +1 more source

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