Results 81 to 90 of about 166,491,988 (249)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Mechanics of Optimal Structural Design for Extreme Loads to Peak System Responses [PDF]

, 2015
Over the past decades, with the development of modern manufacturing and information technology, demands of smart and economical structural designs have been increasing considerably. Central to this engineering issue is that a good structural design needs
Wang, Chien-Kai, Lo, Yuan-Lung, Hou, Kai-Shan, Zhao, Youjun, Cheng, Wei-Jen   +4 more
core  

CFD Simulation of the Interference Effects of Wind Pressures in Building Groups

MATEC Web of Conferences, 2018
The effect of interference is a hot topic in structural wind engineering. In order to investigate the phenomena of this effect, some cases, including single interfered building, double interfered buildings and building matrixes, were simulated by the ...
Sun Yi, Wang Mei, Liu Bowei
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Current Research Topics: Railroad Bridges and Structural Engineering [PDF]

, 2012
Railroad infrastructure must be maintained safely and reliably for both owners and users. Railroad bridge expenditures in particular represent about 10% of the annual capital investment for Class I railroads in the United States (U.S.).
Moreu, Fernando, LaFave, James M.
core  

A review of progressive collapse research and regulations [PDF]

, 2014
History has demonstrated that buildings designed to conventional design codes can lack the robustness necessary to withstand localised damage, partial or even complete collapse. This variable performance has led governmental organisations to seek ways of
Byfield, M.P., Mudalige, Wjesundara, Morison, C., Stoddart, E.   +3 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

FINDING THE STRAIN –STRESS STATE OF ENGINEERING BUILDINGS. OPTIMIZATION OF STRUCTURAL SOLUTIONS

Nauka ta progres transportu, 2010
Industrial pipes are an integral part of the complex structures of enterprises of metallurgical, chemical and other industries from the moment of their advent. Their purpose is to exhaust industrial wastes with residual content of hazardous substances on
V. Ye. Volkova, M. S. Oleynik
doaj  

Structural Vibration Comfort: A Review of Recent Developments

Buildings
With continuous improvements in the social economy and living standards of individuals, the vibration comfort of building structures has gradually been emphasized by academic and engineering communities, such as vehicle-induced vibrations in buildings ...
Weiping Xie, Yumeng Hua
doaj   +1 more source