Results 41 to 50 of about 20,133 (313)

An mass ratio of permanent loads to variable loads of reinforced concrete buildings

Journal of Asian Architecture and Building Engineering
Environmental and resource crises necessitate sustainable development, yet construction lags in material conservation and carbon mitigation. Extensive use of reinforced concrete results in excessive permanent loads and larger building self-weight ...
Wanghu Sun, Yuning Sun, Chen Liu
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Seismic Evaluation and Methods of Rehabilitation of Old Masonry Buildings in the Bay of Kotor (Montenegro)

Applied Sciences, 2021
Old load-bearing masonry buildings exist all around the world. The cultural and architectural heritage value of these buildings and the consciousness of public opinion have led to a need for safeguarding and preservation policies for these ...
Dušan Tomanović, Ljubo Marković, Nebojša Gadžić, Irena Rajković, Julija Aleksić, Tijana Tomanović   +5 more
doaj   +1 more source

Editorial - Proceedings of the Institution of Civil Engineers - Structures and Buildings

, 2021
The June issue of Structures and Buildings is an In Focus issue on The Role of Structural Timber in the Earthquake Protection of Masonry Buildings– Part II that completes the themed issue published in May. This month’s issue features five stimulating technical papers and it is a pleasure for us to introduce them to you.
Giongo, I, Piazza, M, Ingham, J
openaire   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Predicting of vertical displacements of structures of engineering buildings and facilities

Naukovyi Visnyk Natsionalnoho Hirnychoho Universytetu, 2023
Purpose. The research is aimed at solving the tasks of monitoring and assessing the state of an engineering object and determining predictive characteristics in the form of construction of various models of settlement and deformation of a structure based on the results of geodetic measurements, taking into account the space-time interaction of ...
M Sailygarayeva, A Nurlan, K Rysbekov, S Soltabayeva, B Amralinova, Zh Baygurin   +5 more
openaire   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Overturning of Non-Structural Components in Low-Moderate Seismicity Regions

Electronic Journal of Structural Engineering, 2008
The objective of this paper is to review key issues concerned with the proper engineering of non-structural components in buildings for their safe and satisfactory performances in projected seismic conditions in regions of low and moderate seismicity ...
Nelson Lam, Emad Gad
doaj   +1 more source

Exploring the synergy between structural engineering design solutions and life cycle carbon footprint of cross-laminated timber in multi-storey buildings [PDF]

, 2021
Ambrose Dodoo, Nguyen Le Truong, Michael Dorn, Anders Olsson, Thomas K. Bader   +4 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source