Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
THE IMPACT OF LEADERSHIP ON TURNOVER INTENTION: THE MEDIATING ROLE OF ORGANIZATIONAL COMMITMENT AND JOB SATISFACTION [PDF]
Alicia Jia Ping Lim +2 more
doaj +1 more source
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
THE DETERMINANTS OF PURCHASE INTENTION ON COUNTERFEIT SPORTSWEAR [PDF]
Eugene Aw Cheng Xi +1 more
doaj +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
THE IMPACTS OF STRESS, PROJECT-BASED LEARNING ACTIVITIES, AND MOTIVATION ON STUDENTS’ LEARNING
João Alberto Arantes do Amaral +1 more
doaj +1 more source
DO SOCIAL AND COMMERCIAL DESIRES INFLUENCE THE PURCHASING INTENTIONS OF GENERATION Z IN ONLINE SOCIAL SHOPPING? [PDF]
Tang Kin Leong , Huam Hon Tat
doaj +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
PAY SATISFACTION AND ORGANISATIONAL TRUST: AN IMPORTANCE-PERFORMANCE MAP ANALYSIS [PDF]
Gabriel C. W. Gim, Wen-Sing Cheah
doaj +1 more source
A MULTI-MEDIATION MODEL ANALYSIS OF INDUSTRY 4.0, MANUFACTURING PROCESS FACTORS AND GREEN PERFORMANCE UNDER COVID-19 [PDF]
Mahmoud Ramadan Barakat +3 more
doaj +1 more source

