Results 71 to 80 of about 1,045,002 (343)
On the use of Structural Equation Models and PLS Path Modeling to build composite indicators [PDF]
Nowadays there is a pre-eminent need to measure very complex phenomena like poverty, progress, well-being, etc. As is well known, the main feature of a composite indicator is that it summarizes complex and multidimensional issues. Thanks to its features,
Giorgio Russolillo, Laura Trinchera
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Virtuous organization: A structural equation modeling approach [PDF]
For years, the idea of virtue was unfavorable among researchers and virtues were traditionally considered as culture-specific, relativistic and they were supposed to be associated with social conservatism, religious or moral dogmatism, and scientific ...
Majid Zamahani +3 more
doaj
ENHANCING CUSTOMER RETENTION: THE ROLE OF CUSTOMER SATISFACTION AND DELIGHT IN THE AUTHORIZED AUTOMOTIVE AFTER-SALES SERVICE SECTOR [PDF]
This study examines the influence of utilitarian and hedonic experiences, customer engagement, and customer value anticipation on customer retention in the authorized automotive after-sales service sector, using customer satisfaction and customer delight
Choi-Meng Leong +5 more
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
International products and purchase intention in Jordan among consumer ethnocentrism [PDF]
This study attempts to validate the Antecedents of Consumer Ethnocentrism and determine causal relationships between the specified antecedents and customer ethnocentrism in light of customer behavior in a less developed country Jordan.
Abbas, N. Albarq
core
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Market Orientation, Innovativeness, and Performance of Food Companies [PDF]
Food processors have seen escalating levels of competition over the past three decades. An underlying objective of this research is to gain a greater understanding of how food companies thrive in the face of this increased competition.
Dibrell, Charles Clay +2 more
core +1 more source

