How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
QUANTIFYING EMPLOYEES’ WELL-BEING AS THE MEDIATOR FOR ORGANISATIONAL RESILIENCE THROUGH EMPLOYEE-CENTRED CSR: A MODEL COMPARISON APPROACH [PDF]
This study investigates the relationship between Employee-Centred Corporate Social Responsibility (ECCSR) and organisational resilience, focusing on empirically validating the mediating effects through rigorous model comparison approach to enhance the ...
Mei Peng Low, Tat-Huei Cham, Zijie Gao
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
On the Use of Formative Measurement Specifications in Structural Equation Modeling: A Monte Carlo Simulation Study to Compare Covariance-Based and Partial Least Squares Model Estimation Methodologies [PDF]
The broader goal of this paper is to provide social researchers with some analytical guidelines when investigating structural equation models (SEM) with predominantly a formative specification. This research is the first to investigate the robustness and
Ringle, Christian M. +3 more
core +2 more sources
Safety-specific transformational leadership, safety climate and occupational accidents [PDF]
Despite the fact that safety-specific transformational leadership had been reported to have favorable outcomes on workplace safety, there is limited work on identifying its role in decreasing occupational accidents at workplace.
Muhammad Zeeshan Mirza +1 more
doaj
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Meta-analytic structural equation modeling: a primer
Meta-analytic structural equation modeling is a new research field which can help to explain the relationship between a group of variables in several studies by testing structural equation modeling.
Zhenwei Dai
core +1 more source
Absorptive Capacity, Growth Hacking, and Entrepreneurial Performance: PLS-SEM and Necessary Condition Analysis [PDF]
This study aims to examine the role of absorptive capacity as an antecedent of growth hacking and its subsequent impact on entrepreneurial performance among SMEs in Indonesia.
Rizaldi Yusfiarto
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
On Inconsistency of the Overidentification Test for the Model-implied Instrumental Variable Approach
In the context of structural equation modeling, the model-implied instrumental variable (MIIV) approach has been shown to be more robust against model misspecification than the systemwide approaches (e.g., maximum likelihood and least squares).
Jin, Shaobo, Jin, Shaobo,
core +1 more source

