Results 81 to 90 of about 6,834,354 (294)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A structural equation modeling analysis on solvency, operation and profitability of life insurers [PDF]

open access: yes, 2013
textThe abilities of life insurers can be divided and measured from various aspects. Through the use of structural equation modeling, we investigate the relations among solvency, operation ability and profitability in year 1994, 1995 and 1996.
Zhu, Shuangshuang
core  

Factors influencing online purchase intention of millennials and gen z consumers [PDF]

open access: yesJournal of Applied Structural Equation Modeling, 2020
This study examines the factors affecting millennials and generation Z’s purchase intention in online shopping. The variables under investigation, namely, impulse purchase orientation, quality orientation, brand orientation, online trust, and online ...
Nasrul Fadhrullah Isa   +3 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Associations between the classroom learning environment and student engagement in learning 2: A structural equation modeling approach [PDF]

open access: yes, 2012
Purpose This report is about the second of two phases in an investigation into associations between student engagement in classroom learning and the classroom-learning environment.
Cavanagh, R.F.   +3 more
core   +1 more source

Structural Equation Modeling

open access: yes, 2018
This chapter presents structural equation modeling as a tool for conducting research regarding how collections of variables may be related to each other as well as to a particular outcome or even multiple outcomes.
Kenneth Elpus, Peter Miksza
core   +2 more sources

Standardized parameters resulting from structural equation modeling.

open access: yes, 2020
Standardized parameters resulting from structural equation modeling.
Dario Bacchini (3069924)   +2 more
core   +1 more source

A MODIFIED UTAUT IN THE CONTEXT OF M-PAYMENT USAGE INTENTION IN MALAYSIA [PDF]

open access: yesJournal of Applied Structural Equation Modeling, 2021
Kin Leong Tang   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy