Results 1 to 10 of about 334,686 (114)
Controlling the Substrate Specificity of an Enzyme through Structural Flexibility by Varying the Salt-Bridge Density [PDF]
Molecules, 2021 Many enzymes, particularly in one single family, with highly conserved structures and folds exhibit rather distinct substrate specificities. The underlying mechanism remains elusive, the resolution of which is of great importance for biochemistry ...
Juan Huang +6 more
doaj +2 more sources
Structural Flexibility in Metal-Organic Cages [PDF]
Frontiers in Chemistry, 2021 Metal-organic cages (MOCs) have emerged as a diverse class of molecular hosts with potential utility across a vast spectrum of applications. With advances in single-crystal X-ray diffraction and economic methods of computational structure optimisation ...
Andrés E. Martín Díaz +1 more
doaj +2 more sources
Evaluating RNA Structural Flexibility: Viruses Lead the Way [PDF]
Viruses, 2021 Our understanding of RNA structure has lagged behind that of proteins and most other biological polymers, largely because of its ability to adopt multiple, and often very different, functional conformations within a single molecule.
Connor W. Fairman +2 more
doaj +2 more sources
Nickel and GTP Modulate Helicobacter pylori UreG Structural Flexibility [PDF]
Biomolecules, 2020 UreG is a P-loop GTP hydrolase involved in the maturation of nickel-containing urease, an essential enzyme found in plants, fungi, bacteria, and archaea.
Annalisa Pierro +7 more
doaj +2 more sources
An ecological approach to structural flexibility in online communication systems [PDF]
Nature Communications, 2021 Human perceptual and cognitive abilities are limited resources and consequently cheaply available information translates into hypercompetition for rewarding outcomes.
María J. Palazzi +6 more
doaj +2 more sources
WRN structural flexibility showcased through fragment-based lead discovery of inhibitors [PDF]
Nature CommunicationsWRN helicase is an established synthetic lethal target for inhibition in the treatment of microsatellite instability-high (MSI-H) and mismatch repair deficient (MMRd) cancers.
Rachel L. Palte +24 more
doaj +2 more sources
A Study on the Influence of Dominant Parameters Related to Brake Squeal in the Brake System with the Flexible Pad [PDF]
한국정밀공학회지, 2022 The brake squeal noise is a high-frequency noise over 1 kHz range generated by the contact between the brake pad and the disk. The purpose of this paper was to investigate the behavior of the squeal noise characteristics of the brake system from an ...
Eunseok Lee +5 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionPsychrophilic enzymes are a class of macromolecules with high catalytic activity at low temperatures. Cold-active enzymes possessing eco-friendly and cost-effective properties, are of huge potential application in detergent, textiles ...
Ailan Huang +4 more
doaj +1 more source
Some Clues about Enzymes from Psychrophilic Microorganisms
Microorganisms, 2022 Enzymes purified from psychrophilic microorganisms prove to be efficient catalysts at low temperatures and possess a great potential for biotechnological applications.
Roberta Rapuano, Giuseppe Graziano
doaj +1 more source
Natural Sciences, 2021 Porous coordination polymers (PCPs) with pore decoration have been used as materials for excellent storage and separation functions. The cooperative properties of flexible PCPs can be utilized to achieve the separation of mixtures of gaseous molecules ...
Mickaele Bonneau +6 more
doaj +1 more source