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Many enzymes, particularly in one single family, with highly conserved structures and folds exhibit rather distinct substrate specificities. The underlying mechanism remains elusive, the resolution of which is of great importance for biochemistry ...
Juan Huang +6 more
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IntroductionPsychrophilic enzymes are a class of macromolecules with high catalytic activity at low temperatures. Cold-active enzymes possessing eco-friendly and cost-effective properties, are of huge potential application in detergent, textiles ...
Ailan Huang +4 more
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Some Clues about Enzymes from Psychrophilic Microorganisms
Enzymes purified from psychrophilic microorganisms prove to be efficient catalysts at low temperatures and possess a great potential for biotechnological applications.
Roberta Rapuano, Giuseppe Graziano
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Porous coordination polymers (PCPs) with pore decoration have been used as materials for excellent storage and separation functions. The cooperative properties of flexible PCPs can be utilized to achieve the separation of mixtures of gaseous molecules ...
Mickaele Bonneau +6 more
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Some of the most extensively studied marine or estuarine bacteria belong to the genus Vibrio, with Vibrio cholerae being the most notorious species as it is the cause of cholera in humans. V.
Djamila Benrezkallah
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Effect of Structural Flexibility of Wheelset/Track on Rail Wear
To investigate the influence of the structural deformation of the wheelset and track on rail wear in the longitudinal and lateral directions, a rail wear prediction model is established that can calculate the three-dimensional distribution of rail wear ...
Bingguang Wen +4 more
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Fight fire with fire: the need for a vaccine based on intrinsic disorder and structural flexibility
The absence of advancement in finding efficient vaccines for several human viruses, such as hepatitis C virus (HCV), human immunodeficiency virus type 1 (HIV-1), and herpes simplex viruses (HSVs) despite 30, 40, and even 60 years of research ...
Vladimir N. Uversky
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LL-37, a Multi-Faceted Amphipathic Peptide Involved in NETosis
Innate immunity responds to infections and inflammatory stimuli through a carefully choreographed set of interactions between cells, stimuli and their specific receptors.
Marko Radic, Sylviane Muller
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Continued Complexity of Mutations in Omicron Sublineages
The latest SARS-CoV-2 variant of concern (VOC), Omicron (B.1.1.529), has diversified into more than 300 sublineages. With an expanding number of newly emerging sublineages, the mutation profile is also becoming complicated. There exist mutually exclusive
Austin N. Spratt +7 more
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An Insight of RuBisCO Evolution through a Multilevel Approach
RuBisCO is the most abundant enzyme on earth; it regulates the organic carbon cycle in the biosphere. Studying its structural evolution will help to develop new strategies of genetic improvement in order to increase food production and mitigate CO2 ...
Vladimir Camel, Gaston Zolla
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