Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens. [PDF]
Sci Rep, 2021 A major proportion of allergic reactions to hazelnuts ( Corylus avellana ) are caused by immunologic cross-reactivity of IgE antibodies to pathogenesis-related class 10 (PR-10) proteins.
Führer S +7 more
europepmc +2 more sources
Accurate Prediction of Protein Structural Flexibility by Deep Learning Integrating Intricate Atomic Structures and Cryo-EM Density Information. [PDF]
Nat CommunThe dynamics of proteins are crucial for understanding their mechanisms. However, computationally predicting protein dynamic information has proven challenging.
Song X +6 more
europepmc +2 more sources
Evaluating RNA Structural Flexibility: Viruses Lead the Way [PDF]
Viruses, 2021 Our understanding of RNA structure has lagged behind that of proteins and most other biological polymers, largely because of its ability to adopt multiple, and often very different, functional conformations within a single molecule.
Connor W. Fairman +2 more
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Research on the Control Strategy of Hydraulic Shaking Table Based on the Structural Flexibility
IEEE Access, 2019 The frequency response characteristics of the hydraulic shaking table show the same as that of a two degree of freedom (DOF) resonance system due to the structural flexibility of the hydraulic shaking table.
Bing Zhang +6 more
doaj +2 more sources
Structural flexibility of human α-dystroglycan. [PDF]
FEBS Open Bio, 2017 Dystroglycan (DG), composed of α and β subunits, belongs to the dystrophin‐associated glycoprotein complex. α‐DGis an extracellular matrix protein that undergoes a complex post‐translational glycosylation process. The bifunctional glycosyltransferase like‐acetylglucosaminyltransferase (LARGE) plays a crucial role in the maturation of α‐DG, enabling its
Covaceuszach S +6 more
europepmc +9 more sources
An ecological approach to structural flexibility in online communication systems [PDF]
Nature Communications, 2021 Human perceptual and cognitive abilities are limited resources and consequently cheaply available information translates into hypercompetition for rewarding outcomes.
María J. Palazzi +6 more
doaj +2 more sources
Nickel and GTP Modulate Helicobacter pylori UreG Structural Flexibility [PDF]
Biomolecules, 2020 UreG is a P-loop GTP hydrolase involved in the maturation of nickel-containing urease, an essential enzyme found in plants, fungi, bacteria, and archaea.
Annalisa Pierro +7 more
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Structural Flexibility of DNA-RNA Hybrid Duplex: Stretching and Twist-Stretch Coupling. [PDF]
Biophys J, 2019 DNA-RNA hybrid (DRH) duplexes play essential roles during the replication of DNA and the reverse transcription of RNA viruses, and their flexibility is important for their biological functions.
Liu JH +5 more
europepmc +2 more sources
WRN structural flexibility showcased through fragment-based lead discovery of inhibitors [PDF]
Nature CommunicationsWRN helicase is an established synthetic lethal target for inhibition in the treatment of microsatellite instability-high (MSI-H) and mismatch repair deficient (MMRd) cancers.
Rachel L. Palte +24 more
doaj +2 more sources
C7orf59/LAMTOR4 phosphorylation and structural flexibility modulate Ragulator assembly [PDF]
FEBS Open Bio, 2019 Ragulator is a pentamer composed of p18, MP1, p14, C7orf59, and hepatitis B virus X‐interacting protein (HBXIP; LAMTOR 1—5) which acts as a lysosomal scaffold of the Rag GTPases in the amino acid sensitive branch of TORC1 signaling.
Nadia Rasheed +11 more
doaj +2 more sources