Results 11 to 20 of about 4,240,825 (290)

Local structural flexibility drives oligomorphism in computationally designed protein assemblies. [PDF]

open access: yesNat Struct Mol Biol
Many naturally occurring protein assemblies have dynamic structures that allow them to perform specialized functions. For example, clathrin coats adopt a wide variety of architectures to adapt to vesicular cargos of various sizes.
Khmelinskaia A   +19 more
europepmc   +2 more sources

Flexibility-Induced Robustness in Molecular Catalysts for Electrocatalytic CO2 Reduction [PDF]

open access: yes
CO2 electroreduction to produce fuels and chemicals is of great significance. Molecular catalysts offer valuable advantages in light of their well-defined active sites and tunable structural and electronic properties.
Lihong Jing (1467607)   +23 more
core   +6 more sources

Molecular Dynamics Simulations on the Mesophilic Enzyme Vibrio Cholerae Endonuclease I: Salt Effect Study

open access: yesChemistry Proceedings, 2023
Some of the most extensively studied marine or estuarine bacteria belong to the genus Vibrio, with Vibrio cholerae being the most notorious species as it is the cause of cholera in humans. V.
Djamila Benrezkallah
doaj   +1 more source

Effect of Structural Flexibility of Wheelset/Track on Rail Wear

open access: yesLubricants, 2023
To investigate the influence of the structural deformation of the wheelset and track on rail wear in the longitudinal and lateral directions, a rail wear prediction model is established that can calculate the three-dimensional distribution of rail wear ...
Bingguang Wen   +4 more
doaj   +1 more source

Fight fire with fire: the need for a vaccine based on intrinsic disorder and structural flexibility

open access: yesExploration of Immunology, 2022
The absence of advancement in finding efficient vaccines for several human viruses, such as hepatitis C virus (HCV), human immunodeficiency virus type 1 (HIV-1), and herpes simplex viruses (HSVs) despite 30, 40, and even 60 years of research ...
Vladimir N. Uversky
doaj   +1 more source

LL-37, a Multi-Faceted Amphipathic Peptide Involved in NETosis

open access: yesCells, 2022
Innate immunity responds to infections and inflammatory stimuli through a carefully choreographed set of interactions between cells, stimuli and their specific receptors.
Marko Radic, Sylviane Muller
doaj   +1 more source

Continued Complexity of Mutations in Omicron Sublineages

open access: yesBiomedicines, 2022
The latest SARS-CoV-2 variant of concern (VOC), Omicron (B.1.1.529), has diversified into more than 300 sublineages. With an expanding number of newly emerging sublineages, the mutation profile is also becoming complicated. There exist mutually exclusive
Austin N. Spratt   +7 more
doaj   +1 more source

An Insight of RuBisCO Evolution through a Multilevel Approach

open access: yesBiomolecules, 2021
RuBisCO is the most abundant enzyme on earth; it regulates the organic carbon cycle in the biosphere. Studying its structural evolution will help to develop new strategies of genetic improvement in order to increase food production and mitigate CO2 ...
Vladimir Camel, Gaston Zolla
doaj   +1 more source

Structural flexibility of human α-dystroglycan. [PDF]

open access: yesFEBS Open Bio, 2017
Dystroglycan (DG), composed of α and β subunits, belongs to the dystrophin‐associated glycoprotein complex. α‐DGis an extracellular matrix protein that undergoes a complex post‐translational glycosylation process. The bifunctional glycosyltransferase like‐acetylglucosaminyltransferase (LARGE) plays a crucial role in the maturation of α‐DG, enabling its
Covaceuszach S   +6 more
europepmc   +9 more sources

Topological Elasticity of Flexible Structures [PDF]

open access: yesPhysical Review X, 2020
13 pages, 9 attachments for a total of 6 ...
Adrien Saremi, Zeb Rocklin
openaire   +3 more sources

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