Results 121 to 130 of about 4,240,825 (290)
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
A Problem-Specific and Effective Metaheuristic for Flexibility Design [PDF]
Matching uncertain demand with capacities is notoriously hard. Operations managers can use mix-flexible resources to shift excess demands to unused capacities.
Michael Schneider +2 more
core
Brain SciencesFocus structures, a complex aspect of information structure in language, have garnered significant attention in psycholinguistics. The question of whether Chinese preschoolers aged 4–6 years possess the ability to process focus structures in oral ...
Xueqing Tan, Jun Song
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Virtual Flexibility Matrix on Structural Crack Damage Detection
工程科学与技术, 2006 :Because of too small values(from 10-5 to 10-6)of flexibility matrix, it is prone to influencing from noise. Flexibility matrix elements show whole structural information, its maximal changes may not coincide with damage location.
doaj
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C, 1990 ARAI, Fumihito, FUKUDA, Toshio
openaire +2 more sources
Effect of foundation flexibility of concrete moment resistant frame on drift [PDF]
مهندسی و مدیریت ساختThe effects of the foundation flexibility on Structural drift has been considered in concrete moment resisting frames in this paper. The foundation flexibility influences the total base shear reaction and its distribution directly.
Iman Hakamian
doaj
The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex. [PDF]
Nat Commun, 2023 Chen C +8 more
europepmc +1 more source