Results 91 to 100 of about 809,383 (310)

Analysing the Optimal Fund Selection and Allocation Structure of a Fund of Funds

open access: yes, 2023
This thesis aims to investigate different types of optimization methods that can be used when optimizing fund of fund portfolios. Moreover, the thesis investigates which funds that should be included and what their respective portfolio weights should be, in order to outperform the Swedish SIX Portfolio Return Index.
Cederberg, Idun, Cui, Ida
openaire   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Strengthening Romanian banks' role in the European funds absorption [PDF]

open access: yes
This paper has like objective to present the main aspects concerning strengthening romanian banks' role in the european funds absorption. So, we organized our paper in two sections: the role of banks in the absorption of EU funds and the impact of the ...
Cristi SPULBAR   +2 more
core  

Taking stock of structural funds implementation : current challenges and future opportunities [PDF]

open access: yes, 2003
This paper highlights several themes which have informed programme management since IQ-Net meeting in June 2002, held in Lulea, Sweden. First, it provides an overview of the main development in programme implementation and the financial execution of ...
Bachtler, John   +2 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

COST-BENEFIT ANALYSIS – A HELPFUL INSTRUMENT FOR THE ABSORPTION VALUATION OF STRUCTURAL AND COHESION FUNDS IN ROMANIA [PDF]

open access: yes
Starting with the entering in European Union, absorption of structural and cohesion funds seemed to be a challenge for Romania. But unfortunately, after the first half of the programming period, cost-benefit analysis of projects from different ...
Ecaterina Mariana SUCIU   +3 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

TOGETHER OR APART? STRUCTURAL FUNDS AND REAL CONVERGENCE IN THE NEW MEMBER STATES [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2012
The objective of this study is to analyze the relationship between the structural funds provided by the European Union (EU) and the real convergence of the New Member States that joined the EU in 2004.
Tatomir Cristina Flavia, Alexe Ileana
doaj  

Evaluation of Cross-Border Leakages in Community Support Frameworks. The case of Andalusia (Spain). [PDF]

open access: yes
The enlargement of the European Union to 25 members implies that relative position of Andalusia will improve with regard to the new GDP per capita average.
Antonio Morillas   +2 more
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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