Results 121 to 130 of about 809,383 (310)
How Does Sub-National Autonomy Affect the Effectiveness of Structural Funds? [PDF]
Economic and social cohesion between the EU Member States is one of the explicitly stated goals in the Treaty on European Union. The EU’s Structural Funds as a part of the Union’s regional policies are a mechanism of conditional grants that provides co ...
Cornelius Baehr
core
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Six Years in Managing Structural Funds in Romania. Lessons Learned
Transylvanian Review of Administrative Sciences, 2013 The absorption of structural and cohesion funds is one of Romania’s top priorities. Nevertheless, with a very weak absorption rate (11.47% as of December 31st 2012, according to official data), the overall situation is particularly alarming, considering ...
Dragoş JALIU, Crina RĂDULESCU
doaj
REGIONAL CONVERGENCE AND THE IMPACT OF EUROPEAN STRUCTURAL FUNDS OVER 1989-1999: A SPATIAL ECONOMETRIC ANALYSIS [PDF]
This paper estimates the impact of structural funds on the convergence process between 145 European regions over 1989-1999. Since the majority of these funds finance transportation infrastructures, they induce spillover effects, industry relocation and ...
Julie Le Gallo, Sandy Dall'erba
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Effectiveness of structural funds – microlevel perspective (case of Slovakia) [PDF]
Cohesion policy and regional policy as a main part of cohesion policy are the most important policies of European Union. This could also be view from the volume of financial resources allocated for these policies.
Miroslav Å ipikal
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source