Results 131 to 140 of about 814,307 (311)
Effectiveness of structural funds – microlevel perspective (case of Slovakia) [PDF]
Cohesion policy and regional policy as a main part of cohesion policy are the most important policies of European Union. This could also be view from the volume of financial resources allocated for these policies.
Miroslav Å ipikal
core
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
ROMANIAN RURAL DEVELOPMENT AND THE FINANCING POLICY [PDF]
Romania has a large rural areas and a great potential, but the Romanian rural has many economic and social issues. The main idea is that the major risk for the Romanian rural development is generated of the combination between the transition problems ...
Assoc. Prof. Laura Giurcă Vasilescu Ph. D. +1 more
core
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Intelligent Region Management = Intelligent Absorption of EU funds [PDF]
Effective institutions and public administration is a key factor in designing and implementing the growth policy and the economic and social development.
Cornelius Pylak
core
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Difficulties of the EU – the Cohesion Policy Implementation System in the Czech Republic
The article deals with the application of theories of European integration on a case study. In the first part of the article the current state of the Czech-EU structural policy is described.
Filip Capanda
doaj
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source

