Results 121 to 130 of about 814,307 (311)

Provision of Liquidity through the Primary Credit Facility during the Financial Crisis: A Structural Analysis [PDF]

open access: yes
Over the course of the recent liquidity crisis, the Federal Reserve made several changes to its primary credit lending facility such as narrowing the spread between the primary credit rate and the target funds rate and increasing the term of the ...
Erhan Artuç, Selva Demiralp
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Problems of Romanian SMEs with tapping EU structural funds [PDF]

open access: yes
Romanian SMEs can directly benefit from the Sectoral Operational Programme “Increase of Economic Competitiveness” (SOP IEC) and some parts of the Regional Operational Programme (ROP) in the 2007–2013 period.
Gábor HUNYA
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Six Years in Managing Structural Funds in Romania. Lessons Learned

open access: yesTransylvanian Review of Administrative Sciences, 2013
The absorption of structural and cohesion funds is one of Romania’s top priorities. Nevertheless, with a very weak absorption rate (11.47% as of December 31st 2012, according to official data), the overall situation is particularly alarming, considering ...
Dragoş JALIU, Crina RĂDULESCU
doaj  

Conditions for a contribution by the Structural Funds to real convergence of the Recently Acceded Member States [PDF]

open access: yes
The recent EU enlargement poses immense challenges for EU regional policy in terms of increased necessity of priority setting and achieving allocative efficiency.
Michael H. Stierle
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Romanian Pattern in Absorption and Management of European Structural Funds : A Critical Analysis [PDF]

open access: yes
. The decisions in the cohesion policy have a significant impact upon the offer and supply, in a way that, under the influence of the multipliers, they constantly reconfigure the components of the internal consumption (such as investments, private ...
Susanu, Monica
core   +4 more sources

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