Results 161 to 170 of about 809,383 (310)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

A Dual-Mode Flexible Sensor with Capacitive-Resistive Hybrid Response for Bolt Loosening Monitoring. [PDF]

Sensors (Basel)
Ping Y, Li K, Yuan C, Guo D, Yang Y.
europepmc   +1 more source

THE CROSS-BORDER COOPERATION EXPERIENCE BETWEEN ROMANIAN AND HUNGARIAN ECONOMISTS. THE IMPACT OVER THE DEVELOPMENT OF BIHOR HAJDAš-BIHAR EUROREGION [PDF]

This paper analyzes the particular situation of the economists from Bihor and HajdAsa€“Bihar County who are members of different professional organizations and who play an active role in raising the grade of structural funds absorption in the general ...
ChirilÄ? Lavinia Florentina, Dodescu Anca Otilia   +1 more
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

An effective fragment-based dual conditional diffusion framework for molecular generation. [PDF]

Brief Bioinform
Chen H, Shen Y, Li J, Zhao W.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

MPHGNN: metapath-guided heterogeneous graph neural network for miRNA-drug resistance association prediction. [PDF]

Brief Bioinform
Huang G, Peng Y, Wu S, Wei H, Liu S.
europepmc   +1 more source

DETERMINANTS OF INCREASING EU FUNDS ABSORPTION CAPACITY IN ROMANIA [PDF]

The study found that, during the early post-accession years, Romania failed toattract European funds, at least to the same extent to the national contribution at thecommunity budget, registering a net expenditure as an EU member.
George Georgescu
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Revitalizing poly(urea)s via disulfide reconfiguration. [PDF]

Sci Adv
Zong Z, Qu DH, Tian H, Zhang Q.
europepmc   +1 more source