Results 181 to 190 of about 219,271 (347)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

European funds and firm performance: evidence from a natural experiment. [PDF]

open access: yesSmall Bus Econ (Dordr)
Mesquita J   +2 more
europepmc   +1 more source

The implementational analysis of EU Structural Funds: case studies of Cohesion countries

open access: yes, 2006
Europos Sąjungos (toliau – ES) plėtra daugeliu atžvilgių yra unikalus procesas. Lietuvai šiame integracijos procese labai svarbu nagrinėti ne tik artimiausių valstybių kaimynių patirtį, bet ir sugebėti perimti ilgalaikę Vakarų Europos valstybių integracijos tarpvalstybinių derybų patirtį, išmokti derinti interesus, ieškoti ES ir nacionalinių ...
openaire   +1 more source

EU cohesion policy performance: regional variation in the effectiveness of the management of the structural funds

open access: yes, 2020
La efectividad en la absorción de fondos es un desafío permanente para los estados miembros de la UE y, por tanto, resulta necesario analizar la capacidad de absorción de los mismos. Este trabajo aborda la absorción de los recursos de la UE y se centra en un aspecto que hasta ahora ha sido obviado en la literatura anterior: la variabilidad regional en ...
openaire   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

THE IMPACT OF STRUCTURAL FUNDS IMPLEMENTATION IN BIHOR COUNTY. CASE STUDY ON THE REGIONAL OPERATIONAL PROGRAMME 2007-2013 [PDF]

open access: yes
As The County's Development Plan 2007-2013 shows, Bihor county, which through its geographic position and existing local resources, plays a strategic role, of the West gate of Romania, distinguishes through a low unemployment rate, of 2,7% in 2007, on ...
Chirila Lavinia Florentina
core  

Home - About - Disclaimer - Privacy