Results 61 to 70 of about 210,494 (295)
To support efforts to stem the proliferation of chemical weapons (CW), we have curated and structurally annotated CW-control lists from the three key international nonproliferation frameworks: the Chemical Weapons Convention (CWC), the Australia Group ...
S. Costanzi +4 more
semanticscholar +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
1-(4-Methoxyphenyl)-3-phenyl-1H-pyrazol-5-amine
The synthesis of the title compound, C16H15N3O, is regiospecific and single-crystal X-ray diffraction provides the only means of unambiguous structural analysis, with the benzene ring bonded to the imine C atom. The phenyl ring and the essentially planar
Gary S. Nichol +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Structure and unique factorization in concordance groups of links
12 pages, 4 ...
Sato, Kouki, Yasuhara, Akira
openaire +2 more sources
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
(R)-2-Benzyl-4-methylpentyl (R)-2-methoxy-2-(1-naphthyl)propionate
The relative configuration of the alcohol component in the title ester, C27H32O3, has been assigned as (R) from the known configuration of (R)-(−)-2-methoxy-2-(1-naphthyl)propionic acid [(R)-MαNP acid].
Yoshinori Inoue +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Long-term-stability of relationship structure in family groups of common marmosets, and its link to proactive prosociality [PDF]
Cooperatively breeding, group-living common marmosets show differentiated relationships, where more strongly bonded dyads within a group engage more in affiliative interactions than less strongly bonded ones. Intriguingly, recent results suggest that strong bonds do not only occur between breeding partners but between individuals from any sex or status,
Finkenwirth, Christa, Burkart, Judith M
openaire +3 more sources

