Results 111 to 120 of about 85,084 (308)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

A higher invariant for matroids

open access: yes, 1967
The Möbius invariant μ, essential to the classification of surfaces, is less useful in the study of exchange geometries (matroids) because it undergoes sizeable fluctuations as a result of minor structural changes, such as the lengthening of an arc.
Crapo, Henry H.
core   +1 more source

Reliability approach for safe designing on a locking system [PDF]

open access: yes, 2010
The aim of this work is to predict the failure probability of a locking system. This failure probability is assessed using complementary methods: the First-Order Reliability Method (FORM) and Second-Order Reliability Method (SORM) as approximated methods,
ARNOUX, Philippe   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A parametrised version of Moser's modifying terms theorem [PDF]

open access: yes
A sharpened version of Moser's `modifying terms' KAM theorem is derived, and it is shown how this theorem can be used to investigate the persistence of invariant tori in general situations, including those where some of the Floquet exponents of the ...
Wagener, F.O.O.
core  

Geometric criticality in scale-invariant networks

open access: yesPhysical Review Research
Dimension in physical systems determines universal properties at criticality. Yet, the impact of structural perturbations on dimensionality remains largely unexplored.
Lorenzo Lucarini   +2 more
doaj   +1 more source

Classifying invariant structures of step traces

open access: yesJournal of Computer and System Sciences, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Janicki, R.   +3 more
openaire   +5 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Invariant almost contact structure on the real extension of a sphere

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки
The existence of contact and almost contact metric structures invariant under the group of motions on the real extension of a two-dimensional sphere with a Riemannian direct product metric was examined.
M. V. Sorokina, Y. V. Morshchinkina
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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