Results 121 to 130 of about 85,084 (308)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Rotationally Invariant Image Representation for Viewing Direction Classification in Cryo-EM

open access: yes, 2014
We introduce a new rotationally invariant viewing angle classification method for identifying, among a large number of cryo-EM projection images, similar views without prior knowledge of the molecule.
Singer, Amit   +3 more
core   +1 more source

An invariant property of a structured population

open access: yesGenetical Research, 1971
SUMMARYConsidering a single mutant gene in a geographically subdivided finite population, it is shown that the average number of heterozygotes, due to this gene, that appear in the population before fixation or loss of this gene is equal to twice the total population number. This is invariant under the geographical structure of the population.
openaire   +2 more sources

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Geometric structure and properties of linear time invariant\ud multivariable systems in the controller canonical form

open access: yes, 2017
In this paper, we analyse some fundamental structural properties of linear time-invariant multivariable systems in the controller canonical form and present a direct method for the computation of bases and associated friends for output-nulling, input ...
Kazantzidou, C.   +2 more
core   +1 more source

METHOD FOR QUANTITATIVE EVALUATION OF THE EMPIRICAL CONFIRMABILITY OF INVARIANT-ORIENTED SIGNALS IN AUTOMATIC SOFTWARE ERROR DETECTION

open access: yesКомпютерні системи та інформаційні технології
This paper addresses the problem of improving the reliability of automatic error detection in software through the integration of formal invariant analysis and machine learning methods.
Фредерік ГУРАЛЬНИК   +1 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Some Remarks on Consistency and Strong Inconsistency of Bayesian Inference

open access: yes
The paper provides new sufficient conditions for consistent and coherent Bayesian inference when a model is invariant under some group of transformations.
Kociecki, Andrzej
core  

Continuous Invariant-Based Maps of the Cambridge Structural Database.

open access: yes
The Cambridge Structural Database (CSD) played a key role in the recently established crystal isometry principle (CRISP). The CRISP says that any real periodic crystal is uniquely determined as a rigid structure by the geometry of its atomic centers ...
Kurlin, Vitaliy A, Widdowson, Daniel E
core   +1 more source

Invariants of structures

open access: yes
We give a categorification of the notion of a mathematical structure originally given by Bourbaki in their set theory textbook. We show that any isomorphism-invariant property of a finite structure can be computed by counting the number of isomorphic copies of small substructures it contains.
openaire   +2 more sources

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